1. Digitum: Repositorio Institucional de la Universidad de Murcia
  2. Revistas y Congresos
  3. Revistas
  4. Histology and histopathology
  5. Vol.33, nº9 (2018)
Por favor, use este identificador para citar o enlazar este ítem: DOI: 10.14670/HH-11-977

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dc.contributor.authorLi, Zequn-
dc.contributor.authorJia, Wenyu-
dc.contributor.authorNiu, Jun-
dc.contributor.authorZhang, Lining-
dc.date.accessioned2022-05-19T06:23:39Z-
dc.date.available2022-05-19T06:23:39Z-
dc.date.issued2018-
dc.identifier.citationHistology and Histopathology, Vol.33, nº9, (2018)es
dc.identifier.issn1699-5848-
dc.identifier.issn0213-3911-
dc.identifier.urihttp://hdl.handle.net/10201/120203-
dc.description.abstractTumour necrosis factor (TNF)-alpha-induced protein 8-like 2 (TIPE2 or TNFAIP8L2) is a novel identified negative regulator of both innate and adaptive immunity, which participates in immune homeostasis. TIPE2 is expressed in both immune tissues and nonimmune tissues. It is significantly down-regulated in patients with infectious and autoimmune diseases, and the depletion of TIPE2 causes severe inflammatory disease. In recent years, accumulating evidence has shown that TIPE2 serves as an ideal biomarker and as a tumour suppressor in several tumour types. In this review, we summarized the roles and corresponding mechanisms of TIPE2 in immune regulation and different diseases, especially in tumourigenesis.es
dc.formatapplication/pdfes
dc.format.extent10es
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de Biología Celular e Histologíaes
dc.relationSin financiación externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectTIPE2es
dc.subjectExpression profilees
dc.subjectImmune regulatores
dc.subjectInflammatory diseaseses
dc.subjectTumourigenesises
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleUnderstanding the roles of negative immune regulator TIPE2 in different diseases and tumourigenesises
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.doiDOI: 10.14670/HH-11-977-
Aparece en las colecciones:Vol.33, nº9 (2018)

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