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DOI: 10.14670/HH-11-908
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Título: | Recent advances in hypertrophic scar |
Fecha de publicación: | 2018 |
Editorial: | Universidad de Murcia. Departamento de Biología Celular e Histología |
Cita bibliográfica: | Histology and Histopathology, Vol.33, nº1, (2018) |
ISSN: | 1699-5848 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología |
Palabras clave: | Hypertrophic scars Fibroblasts Growth factors Mechanotransduction Extracellular matrix |
Resumen: | Hypertrophic scars (HTS) are predominant diseases after burn and trauma, which cause severe physiological and psychological problems. HTS have been researched for decades, and our knowledge about the mechanisms of HTS formation process has been increasing. However, the effects of currently available prevention and treatment strategies are limited. In this review, we summarize currently known mechanisms and recent studies of HTS, including extracellular matrix, matrix metalloproteinases, fibroblasts, myofibroblasts and their contraction ability, keratinocytes, growth factors, inflammatory and immune response, and stem cell treatment, hoping for a better understanding of HTS generation, development and effective translation to treatment strategies. |
Autor/es principal/es: | Zhang, Julei Li, Yan Bai, Xiaozhi Li, Yuehua Shi, Jihong Hu, Dahai |
URI: | http://hdl.handle.net/10201/118267 |
DOI: | DOI: 10.14670/HH-11-908 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 13 |
Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
Aparece en las colecciones: | Vol.33, nº1 (2018) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Zhang-33-27-39-2018.pdf | 1,45 MB | Adobe PDF | Visualizar/Abrir |
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