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10.14670/HH-11-905
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| Título: | The role of endothelial lipase in lipid metabolism, inflammation and cancer |
| Fecha de publicación: | 2018 |
| Editorial: | Universidad de Murcia. Departamento de Biología Celular e Histología |
| Cita bibliográfica: | Histology and Histopathology, Vol.33, nº1, (2018) |
| ISSN: | 1699-5848 0213-3911 |
| Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología |
| Palabras clave: | Endothelial lipase LIPG Cancer Inflammation Lipid metabolism |
| Resumen: | Endothelial lipase (LIPG) plays a critical role in lipoprotein metabolism, cytokine expression, and the lipid composition of cells. Thus far, the extensive investigations of LIPG have focused on its mechanisms and involvement in metabolic syndromes such as atherosclerosis. However, recent developments have found that LIPG plays a role in cancer. This review summarizes the field of LIPG study. We focus on the role of LIPG in lipid metabolism and the inflammatory response, and highlight the recent insights in its involvement in tumor progression. Finally, we discuss the potential of targeting LIPG in therapeutic strategies. |
| Autor/es principal/es: | Yu, Justine E Han, Shu Yan Wolfson, Benjamin Zhou, Qun |
| URI: | http://hdl.handle.net/10201/118266 |
| DOI: | 10.14670/HH-11-905 |
| Tipo de documento: | info:eu-repo/semantics/article |
| Número páginas / Extensión: | 10 |
| Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
| Aparece en las colecciones: | Vol.33, nº1 (2018) |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| Yu-33-1-10-2018.pdf | 2 MB | Adobe PDF |  Visualizar/Abrir |
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