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DOI:10.14670/ HH-11-845
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| Título: | The expression of Smad signaling pathway in myocardium and potential therapeutic effects |
| Fecha de publicación: | 2017 |
| Editorial: | Universidad de Murcia. Departamento de Biología Celular e Histología |
| Cita bibliográfica: | Histology and Histopathology, Vol.32, nº7, (2017) |
| ISSN: | 1699-5848 0213-3911 |
| Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología |
| Palabras clave: | Myocardial infarction Smad TGF-β BMP |
| Resumen: | Myocardial infarction (MI) is a lifethreatening disease. The expression of Smad proteins in the ischemic myocardium changes significantly following myocardial infarction, suggesting a close relationship between Smad proteins and heart remodeling. Moreover, it is known that the expression of Smads is regulated by transforming growth factor-β (TGF-β) and bone morphogenetic proteins (BMP). Based on these findings, regulating the expression of Smad proteins by targeting TGF-β and BMP in the ischemic myocardium may be considered to be a possible therapeutic strategy for the treatment of myocardial infarction |
| Autor/es principal/es: | Duan, Yongjian Zhu, Wei Liu, Min Ashraf, Muhammad Xu, Meifeng |
| URI: | http://hdl.handle.net/10201/117363 |
| DOI: | DOI:10.14670/ HH-11-845 |
| Tipo de documento: | info:eu-repo/semantics/article |
| Número páginas / Extensión: | 9 |
| Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
| Aparece en las colecciones: | Vol.32, nº7 (2017) |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| Duan-32-651-659-2017.pdf | 1,63 MB | Adobe PDF |  Visualizar/Abrir |
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