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DOI: 10.14670/HH-11-750
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Título: | Immunomodulatory functions of mesenchymal stem cells and possible mechanisms |
Fecha de publicación: | 2016 |
Editorial: | Universidad de Murcia. Departamento de Biología Celular e Histología |
Cita bibliográfica: | Histology and Histopathology, Vol.31, nº9, (2016) |
ISSN: | 0213-3911 1699-5848 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología |
Palabras clave: | Mesenchymal stem cells Immunomodulation Cell therapy Regenerative medicine |
Resumen: | In addition to their well-studied self-renewal capabilities and multipotent differentiation properties, mesenchymal stem cells (MSCs) have been reported to possess profound immunomodulatory functions both in vitro and in vivo. More and more studies have shown that MSCs are capable of interacting closely with almost all subsets of immune cells, such as T cells, B cells, dendritic cells, natural killer cells, macrophages, and neutrophils etc. The immunomodulatory property of MSCs may shed light on the treatment of a variety of autoimmune and inflammation-related diseases. In this article, we will review the studies on the immunomodulatory and anti-inflammatory functions of MSCs and the mechanisms responsible for the interaction between immune cells and MSCs, which could improve the development of promising approaches for cellmediated immune therapies. |
Autor/es principal/es: | Wang, Qing Ding, Gang Xu, Xin |
URI: | http://hdl.handle.net/10201/113323 |
DOI: | DOI: 10.14670/HH-11-750 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 11 |
Derechos: | info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
Aparece en las colecciones: | Vol.31, nº9 (2016) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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Wang-31-949-959-2016.pdf | 1,4 MB | Adobe PDF | Visualizar/Abrir |
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