Por favor, use este identificador para citar o enlazar este ítem: 10.1021/acs.iecr.8b02058

Título: Kinetic study of the enzymatic synthesis of 2-phenylethyl acetate in discontinuous tank reactor
Fecha de publicación: 26-jul-2018
Editorial: AMERICAN CHEMICAL SOCIETY
Cita bibliográfica: Industrial & Engineering Chemistry Research, 2018, 57(33), 11280-11287
ISSN: 0888-5885
Materias relacionadas: CDU::6 - Ciencias aplicadas::66 - Ingeniería, tecnología e industria química. Metalurgia
Palabras clave: 2-phenyl-ethyl acetate
2-phenyl alcohol
vinyl acetate
Novozym® 435
transesterification
kinetics
Resumen: There is increasing interest in new processes to produce aromatics labeled as “natural” and, as a consequence, enzymatic processes, in some organic solvent or in solvent-free medium, have been developed. This paper offers a kinetic study of lipase-catalyzed transesterification for synthesizing 2-phenyl-ethyl acetate in a batch reactor, using Novozym® 435 and hexane as solvent. Influence of five variables on the conversion is studied. A pseudo-first order kinetic model, derived as a simplification of a Bisubstrate Ping-Pong kinetics, is presented. The amount of catalyst was the variable most affecting kinetic and yield, while initial substrate concentration had little effect on the reaction kinetic. Yield increased gradually as the molar ratio increased, and was more pronounced with vinyl acetate than 2-phenethyl alcohol. Michaelis constants of both substrates and maximum reaction rate, for the range of assayed experimental conditions of temperature, stirring speed and enzyme concentration, were determined and compared with others in the literature. Finally, the proposed kinetic model was validated with high correlation coefficients.
Autor/es principal/es: Hidalgo, A.M.
Sánchez, A.
Gómez, J.L.
Gómez, E.
Gómez, M.
Murcia, M.D.
Facultad/Departamentos/Servicios: Departamento de Ingeniería Química
Versión del editor: https://pubs.acs.org/doi/10.1021/acs.iecr.8b02058
URI: http://hdl.handle.net/10201/105522
DOI: 10.1021/acs.iecr.8b02058
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 30
Derechos: info:eu-repo/semantics/openAccess
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Descripción: This document is the Accepted Manuscript version of a Published Work that appeared in final form in [Kinetic study of the enzymatic synthesis of 2-Phenyl-ethyl acetate in discontinuous tank reactor], copyright © American Chemical Society, after peer review and technical editing by the publisher. To access the final edited and published work see [https://pubs.acs.org/doi/10.1021/acs.iecr.8b02058].
Aparece en las colecciones:Artículos: Ingeniería Química

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