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10.1017/S0007114517002951
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Gázquez, Antonio | - |
dc.contributor.author | Ruíz-Palacios, María | - |
dc.contributor.author | Larqué Daza, Elvira | - |
dc.contributor.other | Facultades, Departamentos, Servicios y Escuelas::Facultades de la UMU::Facultad de Biología | es |
dc.contributor.other | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Fisiología | es |
dc.date.accessioned | 2021-02-16T19:33:10Z | - |
dc.date.available | 2021-02-16T19:33:10Z | - |
dc.date.issued | 2017-11-23 | - |
dc.identifier.citation | British Journal of Nutrition, 2017, 118, 981–988 | es |
dc.identifier.issn | 0007-1145 | - |
dc.identifier.issn | 1475-2662 | - |
dc.identifier.uri | http://hdl.handle.net/10201/103402 | - |
dc.description.abstract | The great variety of n-3 long chain polyunsaturated fatty acid sources raises the question of the most adequate for using as a docosahexaenoic acid (DHA) supplement during pregnancy. Placental and fetal availability of different DHA sources remains unclear. We investigated DHA availability in maternal lipoproteins, placenta and fetal tissues in pregnant sows fed DHA as phospholipid (PL) or triglyceride (TG) to identify the best DHA source during this period. Pregnant Iberian sows were fed with diets containing 0.8% DHA of total fatty acids as PL from egg yolk or TG from algae oil during the last third of gestation (40 days). Maternal tissues, placentas and fetal tissues were obtained at delivery and DHA quantified by gas-chromatography. MFSD2a carrier expression was analysed in both placenta and fetal brain by western blotting. Sows fed DHA-PL diet showed higher DHA incorporation in plasma LDL but not in plasma total lipids. No differences were found in DHA content between groups in maternal liver, adipose tissue or brain. Placental tissue incorporated more DHA in both total lipids and PL fraction in sows fed DHA-PL. However, this did not lead to an enhanced DHA accretion either in fetal plasma, fetal liver or fetal brain. MFSD2a expression was similar between both experimental groups. Maternal DHA supplementation during pregnancy in sow either as PL or TG produces similar DHA accretion in fetal tissues but not in placenta. Both fat sources are equally available for fetal brain. | es |
dc.format | application/pdf | es |
dc.format.extent | 25 | es |
dc.language | eng | es |
dc.publisher | CAMBRIDGE UNIVERSITY PRESS | es |
dc.relation | Ámbito del proyecto (Europeo, nacional o regional): regional. Agencia/entidad financiadora: Fundación Séneca Convocatoria: Ayudas para la realización de proyectos de investigación 2009 Nombre del proyecto: Estudio de nuevos ingredientes para el aporte de ácido docosahexaenoico (DHA) a embarazadas Código: 11921/PI/09 Ámbito del proyecto (Europeo, nacional o regional): nacional. Agencia/entidad financiadora: Instituto de Salud Carlos III. Convocatoria: Redes Temáticas de Investigación Cooperativa en Salud (RETICS). Acción Estratégica en Salud 2013-2016 Nombre del proyecto: RED SAMID II Código: RD 12/0026/0015 Ámbito del proyecto (Europeo, nacional o regional): regional. Agencia/entidad financiadora: Fundación Séneca Convocatoria: AYUDAS A LAS UNIDADES Y GRUPOS DE EXCELENCIA CIENTÍFICA DE LA REGIÓN DE MURCIA (PROGRAMA SÉNECA 2014). Nombre del proyecto: Research Group of Excellence CHRONOHEALTH Código: 19899/GERM/15 | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | Docosahexaenoic acid | es |
dc.subject | Supplementation | es |
dc.subject | Phospholipid | es |
dc.subject | Triglyceride | es |
dc.subject | Fetal brain | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::612 - Fisiología | es |
dc.subject.other | CDU::6 - Ciencias aplicadas::61 - Medicina::618 - Ginecología. Obstetricia | es |
dc.title | Docosahexaenoic acid supplementation during pregnancy as phospholipids or triglycerides produces different placental uptake but similar fetal brain accretion in neonatal piglets | es |
dc.type | info:eu-repo/semantics/article | es |
dc.relation.publisherversion | https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/dha-supplementation-during-pregnancy-as-phospholipids-or-tag-produces-different-placental-uptake-but-similar-fetal-brain-accretion-in-neonatal-piglets/0406E65067051DD0439D84DDB8628D95 | es |
dc.identifier.doi | 10.1017/S0007114517002951 | - |
Aparece en las colecciones: | Artículos: Fisiología |
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