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http://dx.doi.org/10.1242/jeb.224063
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Título: | Membrane peroxidation index and maximum lifespan are negatively correlated in fish of genus Nothobranchius |
Fecha de publicación: | 22-abr-2020 |
Editorial: | The Company of Biologists Ltd |
Cita bibliográfica: | Journal of Experimental Biology, 20, 223, jeb224063, 1-5 |
ISSN: | 1477-9145 |
Materias relacionadas: | CDU::5 - Ciencias puras y naturales::57 - Biología |
Resumen: | Lipid composition of cell membranes is linked to metabolic rate and lifespan in mammals and birds but very little information is available for fishes. In this study, three fish species of the short-lived annual genus Nothobranchius with different maximum lifespan potentials (MLSP) and the longer-lived outgroup species Aphyosemion australe were studied to test whether they conform to the predictions of the longevity-homeoviscous adaptation (LHA) theory of aging. Lipid analyses were performed in whole fish samples and peroxidation indexes (PIn) for every PL class and for the whole membrane, were calculated. Total PL content was significantly lower in A. australe and N. korthausae, the two species with the highest MLSP, and a negative correlation between membrane total PIn and fish MLSP was found, this meaning that the longer-lived fish species have more saturated membranes and therefore, a lower susceptibility to oxidative damage, as the LHA theory posits |
Autor/es principal/es: | de Costa J. Barja G. Almaida Pagán, Pedro Francisco |
Facultad/Departamentos/Servicios: | Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Fisiología |
Versión del editor: | https://jeb.biologists.org/content/223/11/jeb224063 |
URI: | http://hdl.handle.net/10201/103088 |
DOI: | http://dx.doi.org/10.1242/jeb.224063 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 16 |
Derechos: | info:eu-repo/semantics/openAccess Atribución-NoComercial-SinDerivadas 3.0 España |
Aparece en las colecciones: | Artículos: Fisiología |
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Fichero | Descripción | Tamaño | Formato | |
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Membrane peroxidation index nothobranchius.pdf | 502,76 kB | Adobe PDF | Visualizar/Abrir |
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