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Título: | The relative effects of severe burn injury and pre- and post-natal protein deprivation on mandibular condyle morphology |
Fecha de publicación: | 2010 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | 61 - Medicina |
Palabras clave: | Undernutrition Burn injury |
Resumen: | The mandible has a mixed embryological origin, and its growth is associated with the secondary cartilage of the condyle process (CP). In this area, growth depends on an array of intrinsic and extrinsic factors that influence protein metabolism. In the present study, we used an adolescent rat model to evaluate the growth and development of the CP under conditions of pre- and postnatal protein deficiency, combined with or without the stress of severe burn injury (BI). We found that protein deficiency severely undermined the growth of the CP, by altering the thickness of its constituent layers. BI is also capable of affecting CP growth, although the effect is less severe than protein deficiency. Interestingly, the summed effect of protein deficiency and BI on the CP is less severe than protein deficiency alone. A possible explanation is that the increased carbohydrates in a hypoproteic diet stimulate the production of endogenous insulin and protein synthesis, which partially compensates for the loss of lean body mass caused by BI. |
Autor/es principal/es: | Caixeta de Oliveira, Bruna Cecília de Oliveira, Flávia Terra Martini, Dorival Duarte Prisco, Cleide Rosana da Silva Riguetti, Marta Maria Aparecido Liberti, Edson de Campos Boldrini, Silvia |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/42566 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 10 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.25, nº1 (2010) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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The relative effects of severe burn injury and pre and postnatal protein.pdf | 9,88 MB | Adobe PDF | Visualizar/Abrir |
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