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Título: | Renal leiomyoma: An immunohistochemical, ultrastructural and comparative genomic hybridization study |
Fecha de publicación: | 2007 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | 616.6 - Patología del sistema genitourinario |
Palabras clave: | Renal leiomyoma Immunohistochemistry |
Resumen: | Renal leiomyoma is a rare neoplasm. We report such a case in a 57-year-old Japanese woman who was found to have a mass in the left kidney. The histological examination disclosed the proliferation of spindle cells showing a benign appearance. Entrapped tubular cells were observed in the peripheral area of the tumor. The immunohistochemical examination of spindle neoplastic cells showed a positive reaction for alpha smooth muscle actin, h-caldesmon, l-caldesmon, calponin, muscle actin, myosin and desmin. Additionally, the ultrastructural examination of the tumor showed membrane caveolae and myofilaments in the cytoplasm. This tumor was considered to show a differentiation into smooth muscle cells. The comparative genomic hybridization of the tumor detected the combined losses of chromosomes 4, 6, 12 and 14 which has not been previously described in renal tumors. Finally, the immunohistochemical panel of smooth muscle markers and ultrastructural and genetic study may be useful in diagnosing renal leiomyoma. |
Autor/es principal/es: | Kuroda, Naoto Inoue, Y. Taguchi, T. Tominaga, A. Hes, O. Michal, Michal Hayashi, Yoshihiro Hiroi, Makoto Shuin, T. Lee, Gang-Hong |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/27615 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 6 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol.22, nº 8 (2007) |
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Renal leiomyoma An immunohistochemical ultrastructural and comparative genomic hybridization study.pdf | 6,48 MB | Adobe PDF | Visualizar/Abrir |
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