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Título: | HLA molecule expression in cutaneous squamous cell carcinomas: an immunopathological study and clinical-immunohistopathological correlations |
Fecha de publicación: | 1993 |
Editorial: | Murcia : F. Hernández |
ISSN: | 0213-3911 |
Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.5 - Piel. Dermatología clínica |
Palabras clave: | HLA-ABC HLA-DR |
Resumen: | A correlation between the lack of MHC class 1 gene expression on murine tumor cells and their ability to grow and metastasize has recently been established. This paper studies HLA-ABC and HLA-DR antigen expression in tumor cells and mononuclear infiltrate of 26 cutaneous squamous cell carcinomas (SCC). Our results showed a heterogeneous expression of HLA class 1 molecules in these tumors. No significant correlation between the degree of HLA class 1 molecule expression and anatomical-clinical parameters was found. Class 11 antigen expression was correlated to the histopathological type and to the degree of cell differentiation. Most mononuclear cells infiltrating the tumor were T-lymphocytes. No correlation with anatomical-clinical parameters was found. |
Autor/es principal/es: | García-Plata, D. Mozos, E. Carrasco, L. Solana, R. |
Forma parte de: | Histology and histopathology |
URI: | http://hdl.handle.net/10201/18399 |
Tipo de documento: | info:eu-repo/semantics/article |
Número páginas / Extensión: | 8 |
Derechos: | info:eu-repo/semantics/openAccess |
Aparece en las colecciones: | Vol. 8, nº 2 (1993) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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HLA molecule expression in cutaneous squamous cell carcinomas an immunopathological study and.pdf | 1,3 MB | Adobe PDF | Visualizar/Abrir |
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