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Título: Salivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren’s syndrome: a pilot study
Fecha de publicación: 20-jul-2018
Editorial: https://link.springer.com/
Cita bibliográfica: Clinical Oral Investigations (2019) 23:1407–1414
ISSN: Print: 1432-6981
Electronic: 1436-3771
Materias relacionadas: Interdisciplinary Laboratory of Clinical Analysis Interlab-UMU, Faculty of Veterinary / Facultad de Medicina Odontologia Medicine,
Palabras clave: Adiponectin
Adenosine deaminase
Biomarker
Clinical signs
Xerostomia
Saliva
Resumen: Objectives To evaluate salivary adiponectin and adenosine deaminase (ADA) in women suffering from Sjögren’s syndrome (SS). Methods Salivary adiponectin and ADA were measured in patients with SS (n = 17) and compared to their values in healthy controls (n = 13) and patients suffering from drug-induced xerostomia (non-SS sicca group; n = 19). A clinical history was made for each patient, patients were examined clinically, and xerostomia inventory (XI) was performed. Results Salivary adiponectin corrected by total protein was higher in patients with SS than in healthy individuals (P < 0.05) or patients with non-SS sicca (P < 0.01) and correlated with XI (r = 0.555; P < 0.05). Salivary ADAwas higher in patients with SS and non-SS sicca compared to controls (P<0.05 in both cases). Conclusion The results of the present study indicate that adiponectin and ADA are increased in the saliva of patients with SS. Clinical relevance Salivary adiponectin corrected by total protein can be a potential biomarker of SS.
Autor/es principal/es: Tvarijonaviciute, Asta
Zamora, Carmen
Martinez-Subiela, Silvia
Tecles, Fernando
Pina, Francisca
Lopez Jornet, Pia
Facultad/Departamentos/Servicios: Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Dermatología, Estomatología, Radiología y Medicina Física
Versión del editor: https://link.springer.com/article/10.1007/s00784-018-2570-3
URI: http://hdl.handle.net/10201/137899
DOI: https://doi.org/10.1007/s00784-018-2570-3
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 8
Derechos: info:eu-repo/semantics/openAccess
Descripción: © 2018. The authors. This document is the Published version of a published Work that appeared in final form in Clinical Oral Investigations. To access the final edited and published work see https://doi.org/10.1007/s00784-018-2570-3
Aparece en las colecciones:Artículos: Dermatología, Estomatología, Radiología y Medicina Física

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