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Título: Evaluation of microvascular density in tumors, pro and contra
Fecha de publicación: 2008
Editorial: Murcia : F. Hernández
ISSN: 0213-3911
Materias relacionadas: 616 - Patología. Medicina clínica. Oncología
Palabras clave: Angiogenesis
Endothelial cell
Resumen: Microvascular density (MVD) counting protocols have become the morphological gold standard to assess the neovasculature in human tumors. This method requires the use of specific markers to vascular endothelium and of immunohistochemical procedures to visualize microvessels. MVD determined in primary tumors is significantly associated with metastasis and prognosis in several tumors and is most predictive in those tumors that induce significant angiogenesis, namely carcinomas of breast and prostate, and haematological malignancies. There is such a wide range of antibodies and suppliers, antigen retrieval methods, designation of high and low vessel count groups, patient study groups and data interpretation, that it is exceedingly difficult to compare results.
Autor/es principal/es: Nico, Beatrice
Benagiano, Vicenzo
Mangieri, Doménica
Maruotti, Nicola
Vacca, Angelo
Ribatti, Doménico
Forma parte de: Histology and histopathology
URI: http://hdl.handle.net/10201/29811
Tipo de documento: info:eu-repo/semantics/article
Número páginas / Extensión: 7
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:Vol.23, nº5 (2008)

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