Publication: Impact of deep endometriosis with and without ovarian involvement on quality of life compared to exclusive ovarian endometriosis
Authors
Marín Sánchez, Pilar ; Martínez-Esparza Alvargonzález, María Concepción ; García Peñarrubia, María del Pilar ; Ruiz Alcaraz, Antonio José ; Arense Gonzalo, Julián Jesús
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Facultad de Biología
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Publisher
Elsevier
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DOI
https://doi.org/10.1016/j.gine.2025.101053
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info:eu-repo/semantics/article
Description
Abstract
Objetivo: Estudiar si hay diferencia en la calidad de vida en pacientes que presentan endometriosis profunda con o sin afectación ovárica (DE) frente a pacientes con endometriosis ovárica exclusivamente (OMA). Materiales y método: Se ha diseñado un estudio prospectivo observacional en pacientes que padecen endometriosis diagnosticadas mediante clínica y pruebas de imagen o confirmación histológica mediante laparoscopia. Las pacientes fueron clasificadas en OMA o DE. Se han evaluado datos clínicos como la escala analógica de dolor, demográficos, antropométricos y la escala de calidad de vida SF12V2. Para el análisis estadístico se ha empleado el sistema IBM SPSS 25.0. Resultados: Se han reclutado 307 pacientes, 109 OMA y 198 DE. Las pacientes con OMA son más jóvenes que las pacientes con DE. La calidad de vida en la esfera física es menor en DE que en OMA (46 ± 11,91 vs. 49,9 ± 9,4; p < 0,02). No se han encontrado diferencias significativas en la esfera mental (41,5 ± 10,2 vs. 42,8 ± 11; p < 0,276). No se han encontrado diferencias significativas en los dos grupos en el dolor basado en la escala analógica del dolor. En cambio, en el dominio de dolor de la escala SF12V2, se encontraron diferencias entre OMA y DE, siendo las cifras menores en la profunda (61,4 ± 32,7 vs. 73,6 ± 28,6; p < 0,001). Conclusión: En la práctica clínica se deberían utilizar escalas de calidad de vida porque aportan conocimiento de cómo afecta esta enfermedad a sus vidas. Las pacientes con endometriosis profunda tienen una peor calidad de vida en la esfera física comparada con la de pacientes con endometriosis ovárica aislada.
Objective: To evaluate potential differences in quality of life between patients with deep endometriosis, with or without ovarian involvement (DE), and those with exclusive ovarian endometriosis (OMA). Material and method.:A prospective observational study was conducted on patients diagnosed with endometriosis through clinical assessment and imaging techniques, or histological confirmation. Patients were labeled as OMA or DE. Clinical data such as pain (visual analogue scale), demographic and anthropometric data, and QoL (SF-12v2 scale) were evaluated. Statistical analysis was performed using IBM SPSS 25.0. Results: A total of 307 patients were enrolled, 109 with OMA and 198 with DE. Patients with OMA were younger than those with DE. QoL in the physical domain was lower in DE compared to OMA (46 ± 11.91 vs 49.9 ± 9.4; p < 0.02). No statistically significant differences were observed in the mental domain (41.5 ± 10.2 vs 42.8 ± 11; p < 0.276). Pain scores on the visual analogue scale did not differ significantly between groups. However, in the pain domain of the SF-12v2 scale, significant differences were found, with lower scores in DE (61.4 ± 32.7 vs 73.6 ± 28.6; p < 0.001). Conclusion: QoL scales should be utilized in clinical practice as they provide valuable insights into how the disease impacts patients’ lives. Patients with deep endometriosis have a poorer QoL in the physical domain compared to those with exclusive ovarian endometriosis.
Objective: To evaluate potential differences in quality of life between patients with deep endometriosis, with or without ovarian involvement (DE), and those with exclusive ovarian endometriosis (OMA). Material and method.:A prospective observational study was conducted on patients diagnosed with endometriosis through clinical assessment and imaging techniques, or histological confirmation. Patients were labeled as OMA or DE. Clinical data such as pain (visual analogue scale), demographic and anthropometric data, and QoL (SF-12v2 scale) were evaluated. Statistical analysis was performed using IBM SPSS 25.0. Results: A total of 307 patients were enrolled, 109 with OMA and 198 with DE. Patients with OMA were younger than those with DE. QoL in the physical domain was lower in DE compared to OMA (46 ± 11.91 vs 49.9 ± 9.4; p < 0.02). No statistically significant differences were observed in the mental domain (41.5 ± 10.2 vs 42.8 ± 11; p < 0.276). Pain scores on the visual analogue scale did not differ significantly between groups. However, in the pain domain of the SF-12v2 scale, significant differences were found, with lower scores in DE (61.4 ± 32.7 vs 73.6 ± 28.6; p < 0.001). Conclusion: QoL scales should be utilized in clinical practice as they provide valuable insights into how the disease impacts patients’ lives. Patients with deep endometriosis have a poorer QoL in the physical domain compared to those with exclusive ovarian endometriosis.
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Citation
Clínica e Investigación en Ginecología y Obstetricia 52 (2025) 101053
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