Publication: Effect of in vitro gastrointestinal digestion on encapsulated and nonencapsulated phenolic compounds of Carob (Ceratonia siliqua L.) pulp extracts and their antioxidant capacity
Authors
Ydjedd, Siham ; Bouriche, Sihem ; López Nicolás, Rubén ; Sánchez Moya, Teresa ; Frontela Saseta, María del Carmen ; Ros Berruezo, Gaspar ; Rezgu, Farouk ; Louaileche, Hayette ; Kati, Djamel-Edine
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Facultad de Veterinaria
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Publisher
American Chemical Society
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DOI
https://doi.org/10.1021/acs.jafc.6b05103
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info:eu-repo/semantics/article
Description
Abstract
To determine the effect of in vitro gastrointestinal digestion on the release and antioxidant capacity of encapsulated and nonencapsulated phenolics carob pulp extracts, unripe and ripe carob pulp extracts were microencapsulated with polycaprolactone via double emulsion/solvent evaporation technique. Microcapsules' characterization was performed using scanning electron microscopy and Fourier transform infrared spectrometry analysis. Total phenolics and flavonoids content and antioxidant activities (ORAC, DPPH, and FRAP) were evaluated after each digestion step. The release of phenolic acids and flavonoids was measured along the digestion process by HPLC-MS/MS analysis. The most important phenolics and flavonoids content as well as antioxidant activities were observed after gastric and intestinal phases for nonencapsulated and encapsulated extracts, respectively. The microencapsulation of carob polyphenols showed a protective effect against pH changes and enzymatic activities along digestion, thereby promoting a controlled release and targeted delivery of the encapsulated compound, which contributed to an increase in its bioaccessibility in the gut.
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Citation
Ydjedd S, Bouriche S, López-Nicolás R, Sánchez-Moya T, Frontela-Saseta C, Ros-Berruezo G, Rezgui F, Louaileche H, Kati DE. Effect of in Vitro Gastrointestinal Digestion on Encapsulated and Nonencapsulated Phenolic Compounds of Carob (Ceratonia siliqua L.) Pulp Extracts and Their Antioxidant Capacity. J Agric Food Chem. 2017 Feb 1;65(4):827-835. doi: 10.1021/acs.jafc.6b05103. Epub 2017 Jan 17. PMID: 28094929.
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