Presence of Aspartate Aminotransferase in peri-implant crevicular fluid with and without mucositis

Sánchez-Pérez, Arturo; Moya Villaescusa, María José; Caffesse, Raúl Guillermo

Publication:
Presence of Aspartate Aminotransferase in peri-implant crevicular fluid with and without mucositis

dc.contributor.author	Sánchez-Pérez, Arturo
dc.contributor.author	Moya Villaescusa, María José
dc.contributor.author	Caffesse, Raúl Guillermo
dc.contributor.department	Dermatología, Estomatología, Radiología y Medicina Física
dc.date.accessioned	2024-09-04T08:43:37Z
dc.date.available	2024-09-04T08:43:37Z
dc.date.issued	2012-04-01
dc.description	© 2012 American Academy of Implant Dentistry. This document is the Published version of a Published Work that appeared in final form in Journal of Oral Implantology (JOI). To access the final edited and published work see https://doi.org/10.1563/AAID-JOI-D-10-00055
dc.description.abstract	The aim of this study was to assess the presence of aspartate aminotransferase (AST) in peri-implant crevicular fluid, with or without clinical signs of mucositis, to determine its predictive diagnostic value, sensitivity, and specificity. The AST levels were determined (at a threshold of 1200 µIU/mL) for 60 clinically successful implants in 25 patients with or without peri-implant mucositis. Samples were taken prior (AST1) to peri-implant probing with a manual constant-pressure probe (0.2 N) and 15 minutes after probing (AST2). Clinical assessments included radiographic determination of preexisting bone loss, probing, and the evaluation of mucositis, plaque, and bleeding upon probing. Analysis was performed at both the level of the implant and the patient as a unit. We detected a significant difference between AST1 and AST2 at both levels. A significant difference was observed at AST1 between implants that bled upon probing and those that did not. However, when we considered the patient as a unit, there were no significant differences. The plaque index was not significant at either level. AST1 had high specificity and positive predictive diagnostic value (80%) for bleeding upon probing. Probing induces a greater release of AST from inflamed tissues compared with healthy tissues in situ but not at the systemic level. At the implant level, the implant position could be responsible for this difference. Aspartate aminotransferase was a reliable predictor of patients with mucositis.	es
dc.format	application/pdf	es
dc.format.extent	9	es
dc.identifier.citation	Joy Oral Implantology, 2012, Vol. 38 (2), pp.115-123
dc.identifier.doi	https://doi.org/10.1563/AAID-JOI-D-10-00055
dc.identifier.issn	Print: 0160-6972
dc.identifier.issn	Electronic: 1548-1336
dc.identifier.uri	http://hdl.handle.net/10201/143582
dc.language	eng	es
dc.publisher	American Academy of Implant Dentistry
dc.relation	Sin financiación externa a la Universidad.	es
dc.relation.publisherversion	https://meridian.allenpress.com/joi/article/38/2/115/6720/Presence-of-Aspartate-Aminotransferase-in-Peri
dc.rights.accessRights	info:eu-repo/semantics/restrictedAccess
dc.subject	Peri-implant crevicular fluid	es
dc.subject	Tissue damage enzymes	es
dc.subject	AST	es
dc.subject	Aspartate aminotransferase	es
dc.subject	Peri-implant probing	es
dc.title	Presence of Aspartate Aminotransferase in peri-implant crevicular fluid with and without mucositis	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es