Publication:
Animal models for disc degeneration-an update

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dc.contributor.authorJin, Li
dc.contributor.authorBalian, Gary
dc.contributor.authorLi, Xudong Joshua
dc.date.accessioned2022-04-18T09:19:16Z
dc.date.available2022-04-18T09:19:16Z
dc.date.issued2018
dc.description.abstractIntervertebral disc degeneration is considered a major cause of back pain that places a heavy burden on society, both because of its effect on the physiology of individuals and its consequences on the world economy. During the past few decades, research findings in the pre-clinical setting have led to a significant increase in the understanding of intervertebral disc degeneration, although many aspects of the disease remain unclear. The goal of this review is to summarize existing animal models for disc degeneration studies and the difficulties that are associated with the use of such models. A firm understanding of the cellular and molecular events that ensue as a result of injuries, as well as environmental factors, could be instrumental in the development of targeted therapies for the treatment of intervertebral disc degenerationes
dc.formatapplication/pdfes
dc.format.extent12es
dc.identifier.doiDOI: 10.14670/HH-11-910
dc.identifier.eisbnHistology and Histopathology, Vol.33, nÂş6, (2018)es
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/119003
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de BiologĂ­a Celular e HistologĂ­aes
dc.relationSin financiaciĂłn externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectDisc degenerationes
dc.subjectAnimal modeles
dc.subjectIntervertebral disces
dc.subjectAnnulus injuryes
dc.subjectLow back paines
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - PatologĂ­a. Medicina clĂ­nica. OncologĂ­aes
dc.titleAnimal models for disc degeneration-an updatees
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.33, nÂş6 (2018)