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Effects of relaxin on the microvasculature of mouse mammary gland

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dc.contributor.authorBani, Gastonees
dc.contributor.authorBani-Sacchi, Tatianaes
dc.contributor.authorBigazzi, Mario
dc.contributor.authorBianchi, Stefano
dc.date.accessioned2011-01-17T12:41:10Z
dc.date.available2011-01-17T12:41:10Z
dc.date.issued1988
dc.description.abstractThe effects of RLX on the microvasculature of the mouse mammary gland are reported. RLX (pure porcine standard NIH-RXN-P1) at a dose of 3 GPU was administered subcutaneously to virgin adult mice ovariectomized 12 days before. The mammary glands were removed 18-20 h after RLX injection and their examination by light microscopy did not reveal any substantial growth-response to the hormone . Histology and morphometry indicated striking dilation of microvessels, especially capillaries. and electron microscopy revealed an increase in the micropinocytotic vesicles, thus suggesting enhanced transendothelial transport of substances. Such phenomena, which were independent of a release of granules by mast cells, may represent an important component of the mammotrophic action of RLX.en_EN
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/17949
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectRelaxines
dc.subjectMammary glandes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleEffects of relaxin on the microvasculature of mouse mammary glandes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 3, nº 4 (1988)