Publication: Ultrastructural changes in the rat pineal gland after sympathetic denervation. Quantitative study
Authors
Calvo, J.L. ; Boya, J. ; García-Mauriño, J.E.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Ultrastructural changes in the rat pineal
gland were studied quantitatively 7 and 60 days after
the sympathetic denervation by bilateral excission or
decentralization of superior cervical ganglia. The surface
occupied by pineal parenchymal cells decreased in rats of
experimental groups with respect to the control group.
Furthermore, profile areas of the cytoplasm, nucleus and
nucleolus of the pinealocytes were also diminished.
Cytoplasmic lipid droplets in the pinealocytes were
markedly decreased in number and size in experimental
rats. As demonstrated by the Kruskal-Wallis H test,
statistically significant differences were found between
rats of the control and operated groups. Rats treated by
superior cervical ganglionectomy or decentralization
showed morphological changes indicating a hypofunctional
pineal gland, although differences were found between
both groups.
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Citation
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