Publication:
Ion mobility spectrometry for the monitoring of volatile biomarkers: A review of clinical applications

Simple item page
dc.contributor.authorClaudia Giménez-Campillo
dc.contributor.authorNatalia Campillo
dc.contributor.authorNatalia Arroyo-Manzanares
dc.contributor.authorPilar Viñas
dc.contributor.departmentQuímica Analítica
dc.date.accessioned2025-10-16T06:09:06Z
dc.date.available2025-10-16T06:09:06Z
dc.date.issued2025-01-07
dc.description.abstractMedicine is constantly evolving to find new and better ways to diagnose and monitor diseases. The detection of volatile organic compounds (VOCs) in clinical samples is emerging as a non-invasive alternative and is loaded with valuable biomedical information. VOCs are potential biomarkers for disease detection and various clinical applications. Ion mobility spectrometry (IMS) has emerged as a valuable analytical technique for this purpose, offering high sensitivity, rapid results and the ability to analyse complex samples. This article provides a comprehensive review of recent developments in the use of IMS for the analysis of VOCs in various types of clinical samples, including exhaled breath, urine, faeces, blood and tissue. The diagnostic and monitoring potential of the VOCs in various diseases, including infectious pathologies, inflammatory diseases and various forms of cancer, was evaluated. It also discusses the future prospects and developments needed to achieve effective integration of IMS into clinical routine.
dc.formatapplication/pdf
dc.identifier.citationGimenez-Campillo, C., Campillo, N., Arroyo-Manzanares, N., & Vinas, P. (2025). Ion mobility spectrometry for the monitoring of volatile biomarkers: A review of clinical applications. TrAC Trends in Analytical Chemistry, 184, 118138.
dc.identifier.urihttp://hdl.handle.net/10201/166689
dc.languageeng
dc.publisherTrends in Analytical Chemistry
dc.relationSpanish MCIN (Project PID2021-123201NB-I00 financed by MCIN/AEI/10.13039/ 501,100,011,033/FEDER, UE)
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.odsObjetivo 3: Salud
dc.titleIon mobility spectrometry for the monitoring of volatile biomarkers: A review of clinical applications
dc.typeinfo:eu-repo/semantics/article
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
1-s2.0-S0165993625000068-main.pdf
Size:
2.19 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.37 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Artículos