Publication: Systematic review and meta-analysis in anatomic pathology: the value of nuclear DNA content in predicting progression in low grade CIN, the significance of the histological
subtype on prognosis in cervical carcinoma
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Date
1999
Authors
Heatley, M.K.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Meta-analysis, though increasingly popular
in clinical medicine, has not found acceptance in
anatomic pathology. This paper argues that, in
combination with a systematic review of the literature,
meta-analysis may be usefully applied to pathological
research and two examples drawn from gynaecological
pathology (the value of nuclear DNA quantitation in
predicting progression in low grade cervical intraepithelia1
neoplasia and the difference in prognosis
between squamous cell carcinoma and adenocarcinoma
of the cervix) are included to illustrate the methods used
and to demonstrate some of the difficulties associated
with these techniques.
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Citation
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