Publication: Chronic gastritis associated with Helicobacter pylori. Correlation between histological and bacteriological findings
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Date
1991
Authors
Paz-Bouza, J.I. ; García, I. ; Abad, M.M. ; Muñoz, Enrique Guillermo ; Rincón, M.R. ; Bullón, A.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Biopsy specimens of gastric and duodenal
mucosa from 326 patients were examined bacteriologically
and histologically to determine the correlation
between chronic gastritis and H. pylori colonization.
H. pylori was identified in 111 (66.5%) patients with
evidence of chronic gastritis and in 97 (82.2%)
individuals who had gastritis associated with other
pathology (gastric o duodenal ulcer, carcinoma o
bulboduodenitis). The spiral bacteria was found more
frequently in specimens with chronic superficial gastritis
(881107) and no significant difference was observed
between the grade of activity of gastritis and H. pylori
colonization. Giemsa stain was the most suitable method
for detecting H. pylori in histological sections. By
electron microscopy the microorganism was seen on the
surface of the gastric mucosa, beneath the mucous layer,
and more occasionally in intercellular junctions and the
gastric pit.
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