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The role of endothelial lipase in lipid metabolism, inflammation and cancer

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dc.contributor.authorYu, Justine E
dc.contributor.authorHan, Shu Yan
dc.contributor.authorWolfson, Benjamin
dc.contributor.authorZhou, Qun
dc.date.accessioned2022-03-23T10:35:23Z
dc.date.available2022-03-23T10:35:23Z
dc.date.issued2018
dc.description.abstractEndothelial lipase (LIPG) plays a critical role in lipoprotein metabolism, cytokine expression, and the lipid composition of cells. Thus far, the extensive investigations of LIPG have focused on its mechanisms and involvement in metabolic syndromes such as atherosclerosis. However, recent developments have found that LIPG plays a role in cancer. This review summarizes the field of LIPG study. We focus on the role of LIPG in lipid metabolism and the inflammatory response, and highlight the recent insights in its involvement in tumor progression. Finally, we discuss the potential of targeting LIPG in therapeutic strategies.es
dc.formatapplication/pdfes
dc.format.extent10es
dc.identifier.citationHistology and Histopathology, Vol.33, nÂş1, (2018)
dc.identifier.doi10.14670/HH-11-905
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/118266
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de BiologĂ­a Celular e HistologĂ­aes
dc.relationSin financiaciĂłn externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectEndothelial lipasees
dc.subjectLIPGes
dc.subjectCanceres
dc.subjectInflammationes
dc.subjectLipid metabolismes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - PatologĂ­a. Medicina clĂ­nica. OncologĂ­aes
dc.titleThe role of endothelial lipase in lipid metabolism, inflammation and canceres
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.33, nÂş1 (2018)