Publication: Effects of particulate matter under behavioral, hematological and biochemical parameters in Wistar rats
Authors
Siebel-de Moraes, Samanta Cristina ; Branca Moron, Victória ; Machado, Aline Belem ; Schmitt, Paula ; Montanari Migliavacca-Osorio, Daniela ; Bolzan-Berlese, Daiane
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Publisher
Universidad de Murcia. Servicio de publicaciones
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DOI
doi.org/10.6018/analesbio.42.11
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info:eu-repo/semantics/article
Description
Abstract
El Material Particulado (MP) puede alterar los procesos cognitivos,
el comportamiento depresivo y hematológico en el modelo animal.
El objetivo fue evaluar los efectos causados por MP en los parámetros conductuales, hematológicos y bioquímicos en un modelo
animal. Se observaron alteraciones en la actividad locomotora de
las ratas, donde hubo una disminución significativa en la locomoción del Grupo 3 (MP10) en comparación con los Grupo 1 (Control)
y Grupo 2 (MP2,5). Con respecto al comportamiento de ansiedad, el
Grupo 3 pasó significativamente más tiempo en brazos abiertos en
comparación con el control y MP2,5. No se observaron cambios hematológicos y bioquímicos. En este estudio, se concluye que, la
exposición a la MP puede causar daño neurológico y, en consecuencia, afectar a otros sistemas.
Particulate matter (PM) can alter the cognitive processes, the depressive behavior, and the hematological profile in animals. This study aimed to evaluate the effects on behavioral, hematological, and biochemical parameters caused by PM in an animal model. A significant decrease in the locomotion activity of Group 3 (PM10) in relation to Group 1 (Control) and Group 2 (PM2.5) was observed. Regarding the anxiety behavior, Group 3 remained significantly the most part of the time in the open arms when compared to the control and PM2.5 groups. No hematological or biochemical alterations were observed among groups. In this study, we concluded that the exposure to particulate matter can cause neurological damages, and consequently, affect other systems.
Particulate matter (PM) can alter the cognitive processes, the depressive behavior, and the hematological profile in animals. This study aimed to evaluate the effects on behavioral, hematological, and biochemical parameters caused by PM in an animal model. A significant decrease in the locomotion activity of Group 3 (PM10) in relation to Group 1 (Control) and Group 2 (PM2.5) was observed. Regarding the anxiety behavior, Group 3 remained significantly the most part of the time in the open arms when compared to the control and PM2.5 groups. No hematological or biochemical alterations were observed among groups. In this study, we concluded that the exposure to particulate matter can cause neurological damages, and consequently, affect other systems.
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Citation
Anales de Biología, vol.42, (2020)
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