Publication:
Changes in the Rhythm of Speech Difference between People with Nondegenerative Mild Cognitive Impairment and with Preclinical Dementia

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Authors
García Meilán, Juan José ; Martínez-Sánchez, Francisco ; Martínez-Nicolás, Israel ; Llorente, Thide ; Carro, Juan
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Publisher
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DOI
https://doi.org/10.1155/2020/4683573
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info:eu-repo/semantics/article
Description
©<2020>. This manuscript version is made available under the CC-B -NC-ND license http://creativecommons.org/licenses/ by-nc-nd /4.0/ This document is the Published, version of a Published Work that appeared in final form in [Behavioural Neurology]. To access the final edited and published work see [https://doi.org/10.1155/2020/4683573]
Abstract
This study explores several speech parameters related to mild cognitive impairment, as well as those that might be flagging the presence of an underlying neurodegenerative process. Speech is an excellent biomarker because it is not invasive and, what is more, its analysis is rapid and economical. Our aim has been to ascertain whether the typical speech patterns of people with Alzheimer’s disease are also present during the disorder’s preclinical stages. To do so, we shall be using a task that involves reading out aloud. This is followed by an analysis of the recordings, looking for the possible parameters differentiating between those older people with MCI and a high probability of developing dementia and those with MCI that will not do so. We found that the disease’s most differentiating parameters prior to its onset involve changes in speech duration and an alteration in rhythm rate and intensity. These parameters seem to be related to the first difficulties in lexical access among older people with AD.
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Citation
Behavioural Neurology, Volume 2020, Article ID 4683573
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