Publication: Giant cell tumor of the ovary. lmmunohistochemical
Authors
Franco, V. ; Florena, A.M. ; Orlando, E. ; Becchina, G.
item.page.secondaryauthor
item.page.director
Publisher
Murcia : F. Hernández
publication.page.editor
publication.page.department
DOI
item.page.type
info:eu-repo/semantics/article
Description
Abstract
Giant cell tumor (GCT) of the ovary ic a rare
condiiion, fouiid almost invariably in the context of a
mucinous iumor and presenting a microscopic picture
indistinguishable frorn GCT of bone. We describe a case
of GCT in the wall of a serous cyst of the ovary. An
iinmunohistocheniicr~l study was performed using a
panel of antibodies to epithelial, niesenchymal and
leukocyte antigens. Mononuclear arid giant tumor cells
were positive for vimentin; CD 68 and LCA were found
only in giant cells whereas actin was only found in
inononuclear tumor cells. The immunophenotypic
profile of the stronial cells of the residual o\!ary was
identical to that of riiononuclear tumor cells.
The pi-esentcd data suggest that GCT of the ovary is
probnbly ri non-neoplastic lesion of the mesenchyinal
stronial cells that react against substances of the
associated tuinor or cyst.
publication.page.subject
Citation
item.page.embargo
Ir a Estadísticas
Sin licencia Creative Commons.