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Delayed extensive brain edema caused bythe growth of a giant basilar apexaneurysm treated with basilar arteryobliteration: a case report

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dc.contributor.authorGarcía Pérez, Daniel
dc.contributor.authorPanero, Irene
dc.contributor.authorEiriz, Carla
dc.contributor.authorMoreno, Luis Miguel
dc.contributor.authorMunarriz, Pablo M.
dc.contributor.authorParedes, Igor
dc.contributor.authorLagares, Alfonso
dc.contributor.authorAlén, José F.
dc.contributor.departmentFarmacología
dc.date.accessioned2026-02-26T11:19:23Z
dc.date.available2026-02-26T11:19:23Z
dc.date.copyright© The Author(s). 2020
dc.date.issued2020-06-06
dc.description.abstractBackground Partially thrombosed giant aneurysms at the basilar apex (BA) artery are challenging lesions with a poor prognosis if left untreated. Here we describe a rare case of extensive brain edema after growth of a surgically treated and thrombosed giant basilar apex aneurysm. Case presentation We performed a proximal surgical basilar artery occlusion on a 64-year-old female with a partially thrombosed giant BA aneurysm. MRI showed no ischemic lesions but showed marked edema adjacent to the aneurysm. She had a good recovery, but 3 months after surgical occlusion, her gait deteriorated together with urinary incontinence and worsening right hemiparesis. MRI showed that the aneurysm had grown and developed intramural hemorrhage, which caused extensive brain edema and obstructive hydrocephalus. She was treated by a ventriculoperitoneal shunt placement. Follow-up MRI showed progressive brain edema resolution, complete thrombosis of the lumen and shrinkage of the aneurysm. At 5 years follow-up the patient had an excellent functional outcome. Conclusions Delayed growth of a surgically treated and thrombosed giant aneurysm from wall dissection demonstrates that discontinuity with the initial parent artery does not always prevent progressive enlargement. The development of transmural vascular connections between the intraluminal thrombus and adventitial neovascularization by the vasa vasorum on the apex of the BA seems to be a key event in delayed aneurysm growth. Extensive brain edema might translate an inflammatory edematous reaction to an abrupt enlargement of the aneurysm.
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dc.identifier.citationBMC Neurol 20, 232 (2020)
dc.identifier.doihttps://doi.org/10.1186/s12883-020-01819-9
dc.identifier.eissn1471-2377
dc.identifier.urihttp://hdl.handle.net/10201/214462
dc.languageeng
dc.publisherBioMed Central
dc.relationSin financiación externa a la Universidad
dc.relation.publisherversionhttps://link.springer.com/article/10.1186/s12883-020-01819-9
dc.rightsAttribution 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectBasilar apex aneurysm
dc.subjectHunterian occlusion
dc.subjectBrain edema
dc.subject.odsNo relacionado con ningún objetivo de desarrollo sostenible
dc.titleDelayed extensive brain edema caused bythe growth of a giant basilar apexaneurysm treated with basilar arteryobliteration: a case report
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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relation.isAuthorOfPublication.latestForDiscovery2f2500a1-1b27-4420-820c-db8c16e79afd
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