Publication: lmmunocytochemical study of the epithelial lining of naturally occurring cysts in the rat intermediate lobe
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Date
1991
Authors
Carbajo, S. ; Carbajo-Pérez, E. ; Hernández, J.L. ; Vázquez, R. ; Carvajal, J.C.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
An immunocytochemical study of the
epithelial lining of naturally occurring cysts in the rat
intermediate lobe (IL) has been carried out. Paraffinembedded
sections, in which cysts were identifiable,
were treated either with anti-serotonin or anti-S-100
protein sera. S-100-positive cells were intermingled with
glandular cells surrounding the cyst lumen. These S-100-
positive cells sent slender cytoplasmic processes as if to
cover the apical surface of neighbouring cells. Rarely
were 5-HT-immunopositive cells seen in the cyst
epithelial lining. Most cells of the marginal layer of the IL
were found reactive either to an S-100 or a-5-HT serum.
The presence of an epithelial lining positive to S-100
protein sera is in keeping with the notion that cysts in the
IL might form as evaginations of the epithelial lining of
the pituitary cleft. The lack of correspondence between
5-HT-positive cells in the marginal layer and the cyst
lining is controversial. A peculiar spatial relationship of
5-HT cells with the vascular network of the IL is
suggested.
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