Person:
Mondéjar López, Pedro Enrique

Profile Picture
Name
Mondéjar López, Pedro Enrique
publication.page.department
Universidad de Murcia. Departamento de Cirugía, Pediatría, Obstetriciay Ginecología
Repository logoRepository logoRepository logoRepository logo

Filters

2019 - 20203
3
3
Reset filters

Settings

Search Results

Now showing 1 - 3 of 3
  • Thumbnail Image
    Publication
    Open Access
    Preschool asthma symptoms in children born preterm: the relevance of lung function in infancy
    (MDPI, 2020-10-18) Sánchez-Solís de Querol, Manuel; Parra Carrillo, María Soledad; Mondéjar López, Pedro Enrique; García Marcos, Patricia W.; García-Marcos Álvarez, Luis Vicente; Cirugía, Pediatría y Obstetricia y Ginecología; Facultades de la UMU::Facultad de Medicina
    Background: The aim of the study is to assess whether lung function of infants born preterm predicts wheezing in pre-school age. Methods: A survey of the core wheezing questionnaire of the International Study on Asthma and Allergy in Children was administered to parents of preterm newborns, to whom lung function tests were performed at a corrected age of six months, and who, at the time of the survey, were between three and nine years of age. Results: Low values of all lung function parameters measured, except FVC, were predictors of wheezing at some time in life, (FEV0.5 OR: 0.62 (95%CI 0.39; 0.995); FEV0.5/FVC OR: 0.73 (0.54; 0.99)) FEF75 OR: 0.60 [0.37; 0.93]; FEF25-75 OR: 0.57 (0.37; 0.89)); and of wheezing in the past year (FEV0.5 OR: 0.36 (0.17; 0.76); FEV0.5/FVC OR: 0.59 (0.38; 0.93); FEF75 OR: 0.38 [0.19; 0.76]; FEF25-75 OR: 0.35 (0.17; 0.70). In addition, FEV0.5/FVC values lower than the lowest limit of normality, were predictive of hospital admissions due to wheezing (OR: 3.07; (1.02; 9.25)). Conclusions: Limited lung function in infancy is predictive of both future wheezing and hospitalization for a wheezing episode.
  • Thumbnail Image
    Publication
    Open Access
    Impact of SARS-CoV-2 infection in patients with cystic fibrosis in Spain: Incidence and results of the national CF-COVID19-Spain survey
    (2020-06-08) Mondéjar López, Pedro Enrique; Quintana-Gallego, Esther; Girón-Moreno, Rosa M.; Cortell-Aznar, Isidoro; Balbuena-Maiz, Marta Ruiz de; Diab-Cáceres, Layla; Prados-Sánchez, Concepción; Álvarez-Fernández, Antonio; García-Marcos, Patricia W.; Peñalver Mellado, Carlos; Pastor-Vivero, M. Dolores; Olveira, Casilda; López-Neyra, Alejandro; Castillo-Corullón, Silvia; Palma-Milla, Samara; Pérez-Ruiz, Estela; Sole-Jover, Amparo; Barrio, M. Isabel; Sánchez-Solís de Querol, Manuel; Asensio de la Cruz, Óscar; CF-COVID19-Spain Registry Group; Cirugía, Pediatría y Obstetricia y Ginecología; Facultad de Medicina
    Background: Given the high incidence of confirmed infection by SARS-CoV-2 and mortality by COVID-19 in the Spanish population, its impact was analysed among persons with Cystic Fibrosis (CF) as a group at risk of a worse evolution. The possible causes of the incidence observed in them are explained and how CF Units have faced this health challenge is detailed. Methods: Retrospective descriptive observational study, for which a Spanish CF Patients with Confirmed COVID- 19 Registry is created, requesting information on number of people affected between 8 March–16 May 2020 and their clinical-demographic characteristics from the CF Units participating in the European Cystic Fibrosis Society Patient Registry (ECFSPR). The accumulated incidence is calculated, compared with that of the general population. Additionally, a survey (CF-COVID19-Spain) is carried out on prevention of SARS-CoV-2 infection, workings of CF Units and possible reasons for the incidence observed. Results: COVID-19 was diagnosed in eight CF patients, one of whom had received a lung transplant. The accu mulated incidence was 32/10000 in CF patients and 49/10000 in the general population. General death rate was 5.85/10000 while no CF patients included in the ECFSPR died. The characteristics of those affected and the results of the survey are described. Conclusions: Despite being considered a disease at high risk of severe COVID-19, the low incidence and mortality in CF patients in Spain contrasts with the figures for the general population. The possible factors that would explain such findings are discussed, with the help of the results of the CF-COVID19-Spain survey.
  • Thumbnail Image
    Publication
    Restricted
    Impact of early caffeine therapy in preterm newborns on infant lung function
    (Wiley, 2019-10-06) Sánchez-Solís de Querol, Manuel; García-Marcos, Patricia W.; Agüera‐Arenas, Juan; Mondéjar López, Pedro Enrique; García-Marcos Álvarez, Luis Vicente; Cirugía, Pediatría y Obstetricia y Ginecología; Facultade de Medicina
    Objective: To know the effect of caffeine therapy on infant lung function in preterm infants with a gestational age less than 31 weeks. Material and Methods: Forced vital capacity (FVC), forced expiratory volume at 0.5 seconds (FEV0.5), and forced expiratory flows were measured by raised volume rapid thoracoabdominal compression technique; functional residual capacity was measured by plethysmography (FRCpleth). Compliance of the respiratory system was measured by a single interruption technique (Crs). The Student t test was used to compare lung function measurements between the two groups: treated versus nontreated with caffeine. A multivariate analysis was carried out considering each and every lung function parameter (z‐score) as the dependent variable; and gender, gestational age, birth weight (z‐score), corrected age, invasive mechanical ventilation (yes/no), and bronchopulmonary dysplasia (BPD) diagnosis (yes/no) as independent ones. Additionally, stratified analyses by BPD diagnosis were performed. Results: The multivariate analysis showed significant higher z‐scores of FVC and FEV0.5 in preterm infants treated with caffeine (P=.004 and P=.024, respectively). This result only being significant in the group of non‐BPD infants (P=.021 and P=.042), after stratifying by BPD diagnosis. Differences were not found in z‐scores of FEV0.5/FVC, FEF75, FEF25‐75, FRCpleth, nor Crs. Conclusion: Lung function (FVC and FEV0.5) is improved in infants born under 31 weeks of gestation when treated with caffeine. This improvement is driven by the group of infants who did not suffer from BPD. Overall, our results show that there is an early beneficial effect of caffeine treatment in infant lung function.
Ir a Estadísticas