Person: Ruiz Roca, Juan Antonio
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Ruiz Roca, Juan Antonio
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Universidad de Murcia. Departamento de Dermatología, Estomatología,Radiología y Medicina Física
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- PublicationOpen AccessOral status of older people in medium to long-stay health and social care setting: a systematic review(BioMed Central, 2021-06-14) Ruiz Roca, Juan Antonio; Martín Fuentes, Dora; Gómez García, Francisco José; Martínez Beneyto, Yolanda; Dermatología, Estomatología, Radiología y Medicina FísicaBackground: Older patients who spend long periods hospitalized or those who are in a situation of institutionalization represent a risk group in this regard, as many of them suffer a degree of dependence and need help to perform the basic tasks of personal care. It is therefore important to learn more of the oral health status of this group of patients in order to make a proper assessment of the situation and to develop protocols for its management. The purpose of the study was to conduct a systematic review to ascertain the oral health status of older people patients admitted to institutions or hospitalized for a long period of time. Methods: a systematic review of the literature published in two different databases (PubMed, Embase and Cochrane Library) was carried out, with 12 different combinations of keywords based on the following selection criteria: studies published in the last 5 years, in English and/or Spanish and/or Portuguese, with samples of ≥30 patients, performed in patients older than 65 years, admitted to any type of institution and/or hospital center for at least 7 days and in which the state of hard and/or soft tissues of the oral cavity were evaluated in some way. The selected articles were subjected to a thorough analysis. Results: The search strategy covered 1.014 articles: 689 from Pubmed and 325 from Cochrane Library. After applying the eligibility criteria, five articles were selected for our review. The level of evidence of the articles was, a sample of 773 patients most of them were women with an average age older than 70 years old. Conclusions: The oral health of patients aged more than 65 is worse than that of the rest population. Long hospital stays or being institutionalized in a residence makes this group susceptible to a worsening of their oral health status. It is necessary to develop protocols for the oral health care of these patients, accompanied by training programs for the personnel responsible.
- PublicationRestrictedIs YouTube a useful tool for oral care in patients with Parkinson's disease?(Wiley, 2020-07-06) Ruiz Roca, Juan Antonio; Martínez-Izquierdo, Alejandro; Mengual-Pujante, Daniel; Pons-Fuster López, Eduardo; López Jornet, María Pía; Dermatología, Estomatología, Radiología y Medicina Física; Facultad de MedicinaIntroduction: To analyze the quality of YouTube videos offering information about oral care in patients with Parkinson’s disease (PD). Background: Regular oral and dental care is essential for good general health and well-being. In this regard, the motor and/or cognitive problems of people with PD can complicate correct daily hygiene. Materials and methods: A systematic review was made of YouTube videos for the terms “Parkinson’s disease,” “dental education,” “oral care,” “dental care,” “oral disease,” “oral status,” and “oral health.” The videos were assessed for content, duration, number of viewings, days since upload, and likes and dislikes. The interaction index and viewing rate were also evaluated. Video quality was rated using a 5-point Likert scale based on the global quality score (GQS). Results: The search identified 620 videos, of which 42 were included in the analysis. The sources of the uploads were universities (n = 15), television channels (n = 8), and other sources (n = 19). Significant differences were recorded according to the source of information in terms of the duration of the videos (P = .021), the number of views (P = .025), viewing rate (P = .028), days since upload (P = .018), likes (P = .048), and dislikes (P = 0.008). Conclusions: GQS is higher for University videos; YouTube videos are an accessible, effective, informative, and educative tool for improving oral quality of life of patients with PD. Relevance to clinical practice: YouTube is increasingly used by patients with chronic disorders, for many reasons, including the desire for a second opinion, the search for support, and a wish to increase personal knowledge of the disease. Likewise, there is a growing interest in the search for information about oral care and coping skills.
- PublicationRestrictedPyostomatitis vegetans. Report of two cases and review of the literature(Elsevier, 2005-04) Ruiz Roca, Juan Antonio; Berini Aytés, Leonardo; Gay Escoda, Cosme; Dermatología, Estomatología, Radiología y Medicina Física; Facultades de la UMU::Facultad de MedicinaPyostomatitis vegetans (PV) is a rare benign chronic mucocutaneous pustular disorder of unknown etiology, though it is usually associated with chronic inflammatory disease of the bowel—particularly ulcerative colitis. At the oral level PV manifests as an exophytic lesion with an erythematous perimeter and a creamy-yellow surface presenting a friable covering membrane which easily disintegrates, giving rise to the development of small ulcers or superficial erosions. The histology shows epithelial acanthosis and superficial ulceration. The underlying connective tissue exhibits neutrophil and eosinophil infiltration, with miliary abscesses in some cases. The present study describes 2 cases of PV associated with ulcerative colitis. The differential diagnosis should be established with Neumann type pemphigus vegetans, since in both cases the lesions are clinically similar and the histology reveals an important eosinophil response, acanthosis, and the formation of intraepithelial miliary microabscesses. The treatment of PV focuses on control of the disease. In the event the orofacial lesions persist, topical oral drugs such as corticoids, with additional antibiotherapy, multivitamin complexes, and nutritional supplements, can be provided.
- PublicationOpen AccessEffect of Photobiomodulation on Atrophic–Erosive Clinical Forms of Oral Lichen Planus: A Systematic Review(MDPI, 2022-11-27) Ruiz Roca, Juan Antonio; López Jornet, María Pía; Gómez García, Francisco José; Marcos Aroca, Paula; Dermatología, Estomatología, Radiología y Medicina FísicaAbstract: Introduction. Oral lichen planus is a chronic autoimmune inflammatory disease of unknown origin, characterized by various clinical forms of which the atrophic–erosive causes patients the greatest symptomatology. For this reason, there are different treatments that improve the associated signs and symptoms. One of these therapies is photobiomodulation (PBM), which, although new, has a high level of acceptance in dentistry based on evidence. However, there are inconsistent results in its application against lichen planus. The aim of this review was to evaluate the effect of photobiomodulation and its effectiveness as a therapeutic alternative for atrophic–erosive lesions. Material and methods. The databases PubMed, Google Scholar and Cochrane Library were searched to identify studies investigating the photobiomodulation treatment in atrophic–erosive lesions of oral lichen planus. A total of 294 articles were identified, published between 2017 and 2022, and then evaluated; 7 articles that met all the inclusion criteria were included in this study. Results. The type of laser light source used in PBM was the diode laser (four cases), the Nd–YAG laser at the same wavelength of 1064 nm (two cases) and the He–Ne laser (one case). The minimum and maximum wavelengths used were 630 nm and 1064 nm, respectively. Most studies used lesions treated with topical corticosteroids as a control group. The follow-up times of the studies were highly variable. Conclusions. Photobiomodulation is a treatment that competently combats oral lichen planus lesions by improving signs and symptoms, with no known adverse reactions so far, which makes it more beneficial compared to more conventional therapies, such as corticosteroids, for which side effects have been found.
- PublicationOpen AccessUse of CBCT and panoramic radiography in the prediction of alterations in sensivity of the inferior alveolar nerve in third molars: a retrospective cross-sectional study(Elsevier, 2024-06-10) Ruiz Roca, Juan Antonio; Rodríguez Molinero, J. A.; Javaloyes Vicente, P.; Pereira Lopes, O.; Gay Escoda, C.; Dermatología, Estomatología, Radiología y Medicina Física; Facultades de la UMU::Facultad de MedicinaObjectives We investigated which type of orthopantomography (OPG) was best able to predict neurological alterations of the inferior alveolar nerve (IAN) during extraction of a lower third molar (3 M). Methods We analysed cone beam computed tomographies (CBCTs) that were performed at a private dental clinic in Cartagena, Spain over five consecutive years. The CBCTs, together with their corresponding OPGs, had been prescribed for the surgical extraction of a lower 3 M. Results We analysed a total of 342 CBCTs and their corresponding OPGs. After explaining the risk of changes in the IAN sensitivity, 37 patients refused to undergo surgical extraction. The incidence of sensitivity alterations in the 332 dental extractions was 62 (19%): 44 were paraesthesias of the IAN, and 18 were associated with darkening of the root and interruption of the cortical line. Conclusion When an OPG revealed darkening of the root and interruption of the cortical line, the risk of contact between the lower 3 M and the IAN—that is, the probability of changes in IAN sensitivity—increased by over three-fold.
- PublicationOpen AccessmiRNA-21 and miRNA-27b expression in saliva of patients with oral lichen planus: a systematic review(MDPI, 2025-06-18) Di Stasio, Dario; Fiori, Fausto; Romano, Antonio; Palmieri, Annalisa; Mosca, Laura; Ruiz Roca, Juan Antonio; López Jornet, María Pía; Lucchese, Alberta; Dermatología, Estomatología, Radiología y Medicina Física; Facultad de MedicinaOral lichen planus (OLP) is a chronic inflammatory disorder of the oral mucosa with a recognized risk of malignant transformation. MicroRNAs, particularly miRNA-21 and miRNA-27b, have been implicated in the pathogenesis and progression of various diseases, including OLP. Their altered expression in saliva may provide diagnostic and prognostic insights for this condition. This systematic review examines the expression profiles of miRNA-21 and miRNA-27b in the saliva of OLP patients to assess their potential as biomarkers. The review was conducted in accordance with PRISMA guidelines and was registered in the PROSPERO database. A comprehensive search was conducted in PubMed, Embase, and Scopus using specific keywords. Retrieved titles and abstracts were screened based on predefined eligibility criteria, and relevant studies were analyzed. The initial search identified 71 studies. After screening, 17 abstracts were selected for full-text review. Following evaluation, 11 studies were excluded, resulting in 6 studies being included. Findings indicate a consistent upregulation of miRNA-21 and a downregulation of miRNA-27b in OLP saliva samples. These alterations suggest a potential role in disease pathogenesis and risk assessment. The dysregulation of miRNA-21 and miRNA-27b in OLP underscores their potential as salivary biomarkers for diagnosis and disease monitoring. Moreover, the non-invasive nature of salivary miRNAs offers promising clinical applications, enhancing early detection and personalized management strategies for OLP.
- PublicationRestrictedEvaluation of endovenous sedation using BIS monitoring in dentistry. A systematic review(Medicina Oral, S.L., 2020-07-01) Lozano Carrascal, Naroa; Pérez García, Silvia; Ruiz Roca, Juan Antonio; López Jornet, María Pía; Gargallo Albiol, Jordi; Dermatología, Estomatología, Radiología y Medicina Física; Facultades de la UMU::Facultad de MedicinaBackground: The aim of the present review was evaluate the utility and validity of the Bispectral Index (BIS) in dental treatment carried out under endovenous sedation, and compare its efficacy with clinical sedation scales.Material and Methods: Electronic and manual literature searches were conducted by two independent reviewers for articles published up to April 2017 in several databases, including Medline and Cochrane Library.Results: Sixteen articles met the inclusion criteria. A correlation was identified between BIS and clinical sedation scales. A BIS range between 75 and 84 showed a high probability of corresponding to an Observer’s Assessment of Alertness and Sedation Scale (OAA/S) value of 3; a scored 3 on the Ramsay scale corresponds around 85 on the BIS; while BIS values between 57 and 64 corresponded to a University of Michigan Sedation Scale value of 3. BIS monitoring provides continuous measurement of the patient’s hypnotic state or state of consciousness, awareness, and recall. It proved impossible to perform an analysis of statistical data drawn from the studies reviewed due to the disparity of inclusion criteria among the works.Conclusions: BIS for sedation monitoring might make possible to evaluate sedation levels objectively in real time, reducing the dose of the sedative required, increasing safety, and minimizing secondary effects.
- PublicationOpen AccessHemodynamic and ventilatory changes in pediatric patients with special needs: a comparative clinical study(Medicina Oral S.L., 2022-08) Pérez García, Silvia; Ruiz Roca, Juan Antonio; Añez, Cristobal; López Jornet, María Pía; Gargallo Albiol, Jordi; Dermatología, Estomatología, Radiología y Medicina Física; Facultades de la UMU::Facultad de MedicinaBackground: Very limited data are available on the hemodynamic and ventilatory changes during sedation and general anesthesia using bispectral index (BIS) monitoring in intellectually disabled children. The purpose was to determine the hemodynamic and ventilatory changes after propofol and sevoflurane administration in children with special needs (CSN) versus healthy children (HC) during dental treatment. Material and methods: Forty pediatric patients needing dental treatment were allocated into two groups: children without systemic disease (healthy children [HC]) and mentally disabled children (children with special needs [CSN]). Sevoflurane in oxygen (100% oxygen, 5 l/min) and continuous propofol infusion (target-controlled infusion [TCI], 2 µg/ml) were used as sedative agents, and 2% lidocaine with 1:80,000 adrenaline was used as local anesthesia in both groups. Heart rate (HR), oxygen saturation (SaO2), respiratory rate (RR), exhaled carbon dioxide (CO2), blood pressure (BP) and bispectral monitoring (BIS) values were recorded during the entire dental treatment procedure. Results: A statistically significant decrease in systolic BP, diastolic BP and RR was observed, with no significant differences between the healthy and disabled groups. In contrast, the HR and BIS values were lower in the CSN group than in the healthy patients (p ≤ 0.05). Conclusions: Patients with special needs had lower HR and BIS values than healthy patients, while BP, SaO2 and exhaled CO2 showed similar results in both groups. Key words:Bispectral index, hemodynamic changes, ventilatory changes, pediatric patients, special needs.
- PublicationRestrictedDental extractions management in Bernard-Soulier syndrome(Lippincott, Williams & Wilkins, 2015-09) Ruiz Roca, Juan Antonio; Oñate Sánchez, Ricardo Elías; Cabrerizo Merino, María del Carmen; Rodríguez Lozano, Francisco Javier; Dermatología, Estomatología, Radiología y Medicina Física; Facultad de Medicina
- PublicationOpen AccessClinical and pathological features of osteosarcomas of the jaws: a retrospective study(MDPI, 2024-05-23) Rodriguez-Molinero, Jesús; Pozo-Kreilinger, José Juan; Ruiz Roca, Juan Antonio; López-Sánchez, Antonio Francisco; Cebrian-Carretero, José Luis; Dermatología, Estomatología, Radiología y Medicina Física; Facultad de MedicinaIntroduction: Osteosarcomas of the jaw (OSJs) are rare tumors with distinct characteristics from osteosarcomas affecting other bones. This study aims to analyze the clinical, pathological, and therapeutic characteristics of OSJs. Methods: A retrospective, descriptive cross-sectional study including patients diagnosed with OSJ registered at the “La Paz” University Hospital, Madrid, was performed. Results: Data of eight patients with a diagnosis of OSJ were obtained during the study period of 22 years (2002–2024). The mean age of the patients was 41 years. The distribution was 1:1 between the maxilla andmandible. Painful inflammation asthemostfrequentclinical manifestation. Conventional osteoblastic osteosarcoma was the most predominant histological type. Survival rate at 5 years was 50%, which decreased to 25% at 10 years. Conclusions: OSJs differ from conventional osteosarcomas of long tubular bones. Surgery continues to be the mainstay of treatment. However, more studies are needed through which more standardized protocols can be proposed for adjuvant therapeutic management.
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