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García-Estañ López, Joaquín

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García-Estañ López, Joaquín
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Universidad de Murcia. Departamento de Fisiología
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  • Publication
    Open Access
    Effects of flavonoids in experimental models of arterial hypertension
    (Bentham Science Publishers, 2021-08-12) Marín Atucha, Noemí; Romecín, Paola; Vargas, Félix; García-Estañ López, Joaquín; Fisiología; Facultades de la UMU::Facultad de Medicina
    Flavonoids are a class of substances of a vegetal origin with many interesting actions from the point of view of human disease. Interest in flavonoids in the diet has increased in recent years due to the publication of basic, clinical and epidemiological studies that have shown a whole array of salutary effects related to intake of flavonols and flavones as well as a lower morbility and mortality of cardiovascular diseases. Since arterial hypertension is the most common modifiable risk factor for cardiovascular diseases, this review will focus mainly on the effects of flavonoids on the cardiovascular system with relation to the elevation of blood pressure. Its antihypertensive effects as well as the many investigations performed in experimental models of arterial hypertension, are reviewed in this mini-review.
  • Publication
    Open Access
    Platelet function and microvesicle generation in patients with hemophilia A
    (Wiley, 2021-01-19) Melero Amor, Antonia; Romecín, Paola; Iyú Espinosa, David; García Bernal, David; García Navaro, Esther; Moraleda Jiménez, José María; García-Estañ López, Joaquín; García Candel, Faustino; Marín Atucha, Noemí; Fisiología
    Our results do not support any effect of FVIII on platelet function in patients with severe HA treated under the regime of prophylaxis