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García Carrasco, José Manuel

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García Carrasco, José Manuel
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Universidad de Murcia. Departamento de Ingeniería y Tecnología de Computadores
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  • Publication
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    Application of YOLOv8 and a model based on vision transformers and UNet for LVNC diagnosis: advantages and limitations
    (Springer, 2025-04-25) Haro Orenes, Salvador de; González Férez, María Pilar; García Carrasco, José Manuel; Bernabé García, Gregorio; Ingeniería y Tecnología de Computadores
    Hypertrabeculation or left ventricular non-compaction (LVNC) is a cardiac condition that has recently been recognized. While several methods exist for accurately measuring the trabeculae in the ventricle, there is still no consensus within the medical community regarding the optimal approach. In previous work, we introduced DL-LVTQ, a tool based on a UNet convolutional neural network designed to quantify the trabeculae in the left ventricle. In this paper, we present an expanded dataset that includes new patients affected by a cardiomyopathy known as Titin, necessitating the retraining of the models involved in our study on this updated dataset to accurately infer future patients with this condition. We also introduce ViTUNet, a hybrid architecture that aims to merge the benefits of UNet and Vision Transformers for precise segmentation of the left ventricle. Furthermore, we train a YOLOv8 model to detect the left ventricle and integrate it with the hybrid model to focus segmentation on a region of interest around the ventricle. Regarding the precision quality achieved by ViTUNet using YOLOv8, results are quite similar to those obtained by the DL-LVTQ tool, suggesting that the dataset is a limiting factor in our improvement. To substantiate this, we conduct a detailed analysis of the MRI slices in the current dataset. By identifying and removing problematic slices, results significantly improve. The introduction of a YOLOv8 model alongside a deep learning model presents a promising approach.
  • Publication
    Open Access
    A Data-Centric Algorithmic Pipeline for Enhancing Cardiac MRI Segmentation Using ViTUNeT and Quality-Aware Filtering
    (MDPI, 2026-03-06) Salvador de Haro; Jesús Cámara; González Férez, María Pilar; José Manuel García; García Carrasco, José Manuel; Bernabé García, Gregorio; Ingeniería y Tecnología de Computadores; Facultades de la UMU::Facultad de Informática
    The performance of deep-learning-based segmentation models is strongly dependent on the quality of the input data, which is frequently heterogeneous or degraded in real-world medical imaging scenarios. This work presents a data-centric algorithmic pipeline designed to improve cardiac MRI segmentation accuracy through systematic image enhancement and automatic slice-quality filtering. The proposed method is formalized as deterministic algorithm that combines image processing and supervised learning components. The approach integrates a contrast- and structure-preserving enhancement stage, based on bilateral filtering and adaptive histogram equalization, with a quality-aware selection algorithm. Slice quality is assessed using anatomical attributes extracted via YOLOv11sbased localization and a supervised classification model trained to identify diagnostically reliable images. When applied to transformer-based segmentation architectures such as ViTUNeT, the pipeline yields consistent improvements across all evaluation metrics without increasing model complexity or training cost. These findings emphasize the importance of algorithmic data curation as an effective strategy for enhancing robustness and stability in deep-learning segmentation pipelines and demonstrate the broader applicability of the proposed approach to computer-vision tasks involving heterogeneous or low-quality image datasets.
  • Publication
    Open Access
    A Comparative Analysis of Machine Learning and Deep Learning Approaches for Multiclass Nucleus Classifcation in Histological Images
    (Wiley, 2026-01-30) Sánchez-Torres, Antonio Luis; García-Salmerón, Jesús ; González Férez, María Pilar; Bernabé García, Gregorio; García Carrasco, José Manuel; Ingeniería y Tecnología de Computadores; Kalapraveen Bagadi; Facultades de la UMU::Facultad de Informática
    Precisely classifying cells in histological images is critical for early cancer diagnosis and tumor assessment. Traditional manual methods are time-consuming and labor-intensive for histopathologists, driving the development of automated approaches using machine learning (ML) and deep learning (DL). Convolutional neural networks (CNNs) and, more recently, vision transformers (ViTs) have demonstrated signifcant potential in addressing the challenges of cell classifcation by leveraging their ability to automatically extract and learn complex features from histological images. In this work, we evaluate multiple classifcation architectures applied to stained histological images to determine their efectiveness in identifying cancerous cells. We compare traditional ML models, which rely on manually extracted features such as shape and texture, against two DL-based classifers: a CNN-based model (ResNet50) and a ViT-based model. To optimize ML models, we apply principal component analysis (PCA) to refne feature selection. Meanwhile, DL models are trained on cropped cell images using two preprocessing strategies: one that includes additional surrounding cellular context and another that uses only the cell pixels. Additionally, we investigate class balancing strategies, including downsampling and oversampling through data augmentation, to mitigate the efects of dataset imbalance. Experimental results highlight the clear advantage of DL models over traditional ML approaches. ResNet50 consistently delivers robust and reliable performance across diferent preprocessing strategies, confrming its efectiveness for histopathological classifcation tasks. Meanwhile, ViTs achieve results that are comparable to those of CNNs while demonstrating a distinct advantage in classifying underrepresented nucleus classes, likely due to their ability to capture long-range dependencies. Furthermore, incorporating the surrounding cellular environment signifcantly improves classifcation accuracy, underscoring the importance of contextual information in distinguishing between diferent types of nuclei.