Digitum Colección:
http://hdl.handle.net/10201/17693
2024-03-28T18:49:00ZUlmtrastructuroef the chronically vagotomised atrial
myocardiu m in t he mon key (Macaca fascicularis)
http://hdl.handle.net/10201/18133
Título: Ulmtrastructuroef the chronically vagotomised atrial
myocardiu m in t he mon key (Macaca fascicularis)
Autor/es principal/es: Wong, W. C.; Yick, T. Y.; Ling, E. A.
Resumen: The ultrastructure of the atrial myocardium
in the monkey (Macaca fascicularis) was studied after
bilateral cervical vagotomy and survival times of 100,175
and 367 days. Changes were observed in the nucleus and
the cytoplasm of the myocyte. Sequestered within the
nuclei of the affected myocytes were cytoplasmic
organelles and inclusions. In the late stages, there was a
tendency towards condensation and margination of the
heterochromatin. Changes in the cytoplasm included
increased glycogen, mitochondrial degeneration and
myofibrillar disorganisation and degeneration. There
was increased collagen and mononuclear cell infiltration
in the extracellular space in the later stages. This study
has shown that the long term structural integrity of the
atrial myocyte depends on an intact vaga1 innervation.
The survival of the monkey after chronic bilateral
vagotomy suggests that this nonhuman primate is
a suitable model for functional studies of the
parasympathetically denervated heart.1989-01-01T00:00:00ZUltrastructure of atrial and ventricular myocytes of
newborn rats: evidence for the existence of specific
atrial granule-like organelles in the ventricle
http://hdl.handle.net/10201/18132
Título: Ultrastructure of atrial and ventricular myocytes of
newborn rats: evidence for the existence of specific
atrial granule-like organelles in the ventricle
Autor/es principal/es: Venance, Shannon L.; Pang, Stephen C.
Resumen: The present study examined the ultrastructure
of atrial and ventricular myocytes from the heart of
newborn rats. It was found that, despite former reports
stating that ventricular myocytes in adults do not contain
cytoplasmic granules, specific atrial granule-like
organelles are present in the ventricles of rats at birth.
The presence of these granules together with the
relatively underdeveloped contractile apparatus and
extensive Golgi complex suggests that the ventricular,
like the atrial, myocytes may have an endocrine function
before or at birth. Further study is required to determine
whether these ventricular cytoplasmic granules contain
the same atrial natriuretic peptide species known to be
present in the atrial specific granules.1989-01-01T00:00:00ZThe value of conjunctival biopsy in childhood cystinosis
http://hdl.handle.net/10201/18131
Título: The value of conjunctival biopsy in childhood cystinosis
Autor/es principal/es: Cruz-Sánchez, F. F.; Cervós-Navarro, J.; Rodríguez-Prados, S.; Lennert, T.
Resumen: Cystinosis is frequently presented with
cystine storage in the cornea and cnnjiinctiva. and the
diagnosis can be established by slit-lamp esamination. It
can also be confirmed by elcctron microscopy of a
conjunctival biopsy .
The present paper reports on n 16-nionth-old boy with
Fanconi's syndronie. in whoni the slit-lanip examination
did not show crystal deposits of cystinc in the
conjunctiva. The ~iltrastructurals tudj,o f the conjunctival
biopsy demonstruted polygonal crystals within douhle
mcmbrane-liniited organelles located in fibrobliists.
Similar crystals were subsequently found in a hidney
biopsy. We therefore think that conjunctival biopsy is a
valuable diagnostic tool prior to pcrforming renal
biopsy, even in cases with negativc findings hy
ophthalmologic examination.1989-01-01T00:00:00ZThe histological and the histopathological pattern
of conjunctival rhinosporidiosis associated with
papillomavirus infection
http://hdl.handle.net/10201/18130
Título: The histological and the histopathological pattern
of conjunctival rhinosporidiosis associated with
papillomavirus infection
Autor/es principal/es: Sunbal, M. S. Noor; Al-Ali, Saad Y.
Resumen: The present study describes for the first time,
the clinical, light and electron microscopic findings of
two cases of conjunctival rhinosporidiosis. One was with
concurrent infection of papillomavirus. Investigations at
the ultrastructural leve1 have provided additional
information on the development of Rhinosporidium
seeberiand would suggest that the formation of the wall
of this organism is a continuous morphological and
biochemical spectrum throughout its cytological
maturation. The current observation on the wall
formation is probably a modification of the classical
pattern as an environmental protection carried out by the
fungus against the virus. In contradistinction to the usual
histopathological picture of rhinosporidiosis, the case
with the viral infection lacked the characteristic marked
inflammatory reaction. This finding, together with the
relatively short interval of the frequent recurrences of
this lesion, have led us to postulate the presence of a
localised acquired immune deficiency state. It is possible
that this local immune deficiency may be caused by an
immunosuppression mechanism. This is probably
mediated by papillomavirus andlor due to the weak
antigenicity of the host virus-infected cells which contain
only copies of viral DNA in an unintegrated form.1989-01-01T00:00:00Z