Histology and histopathology Vol. 3, nº 1 (1988)
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- PublicationOpen Accesslmmunocytochemical localization of parathyroid hormone in rabbit parathyroid glands(Murcia : F. Hernández, 1988) Shizuko Shoumura; Noriko Ishizaki; Shoichi Emura; Yuji Iwasaki; Tomo Yamahira; Hideo IsonoImmunocytochemical localization of parathyroid hormone was examined in the rabbit parathyroid gland by means of protein A-gold technique. Protein A-gold particles were observed on the secretory granules and the large secretory granules thought to be storage granules. No protein A-gold particles were observed on cisternae of the endoplasmic reticulum and the Golgi apparatus
- PublicationOpen AccessUltrastructural computerized morphometry of platelets in chronic myelogenous leukemia making use of ultra-thin sections and freeze-fracture procedure a preliminary approach(Murcia : F. Hernández, 1988) Bianciardi, G.; Battistelli, S.; Toti, P.; Vallesi, G.; Weber, G.Biochemical and morphological data have shown that the circulating platelets are deeply altered in patients with chronic mielogenous leukemia. In this report we describe the results of ultrastructural morphometry performed by means of a computerized device of the platelet shape (ultra-thin sectioned platelets) and of the platelet plasma-membrane (freezefractured platelets). Platelets appeared deeply modified: reduced mean platelet area and perimeter, increased surface density of the openings of the surface connected canalicular system, abnormal features of the platelet cytoplasm and some aspects of platelets joined together even if with heterogeneity in these findings did appear from patient to patient.
- PublicationOpen AccessUltrastructural pathologic changes of rat extraembryonic visceral endodermal cells exposed to teratogenic antibodies in vivo(Murcia : F. Hernández, 1988) Leung, C.C.K.; DeSha, D.L.; Bui, L.; Cheewatrakoolpong, B.
- PublicationOpen AccessNeuron specific enolase-positive breast carcinomas(Murcia : F. Hernández, 1988) Erikstein, Bjerrn; Nesland, Jahn M.; Ottestad, Lars; Lund, Eiliv; Johannessen, Jan VicentsNinety-eight patients treated for breast carcinomas were followed from 54 to 75 months after primary diagnosis. All had undergone a modified radical mastectomy with removal of axillary lymph nodes. 36 breast carcinomas were NSE-positive and 62 were negative. NSE-positive tumours were significantly more frequently estrogen receptor-positive than the NSEnegative tumours, and the estrogen receptor values were higher in the NSE-positive groups. Patients with NSE-positive tumours and patients with NSE-negative tumours did not differ with regard to presence of lymph node metastases at the time of primary surgery. However, the study showed that patients with NSE-positive tumours had a tendency towards more lymph node metastases after primary surgical intervention, but a better outcome than patients with NSE-negative tumours and metastases. This study, with a 5-year follow up, failed to demonstrate any major prognostic significance of immunostaining for NSE.
- PublicationOpen AccessHepatitis B core and surface antigens and delta agent in chronic liver disease in Kuwait(Murcia : F. Hernández, 1988) Al-Adnani, M. S.
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