Browsing by Subject "Western lifestyle"

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    Diet: a specific part of the western lifestyle pack in the asthma epidemic
    (MDPI, 2020-07-01) Frontela Saseta, María del Carmen; García-Marcos Álvarez, Luis Vicente; González Bermúdez, Carlos Alberto; Tecnología de Alimentos, Nutrición y Bromatología
    The Western lifestyle is a complex concept that includes the diet as the main axis of di erent factors which contribute to a detrimental e ect on health, lower life expectancy and low quality-of-life. This type of diet is characterized by being high in calories, mainly provided by saturated fats, and rich in sugars that can lead to changes in immune cells and their responsiveness, by di erent mechanisms that have yet to be totally clarified. Inflammatory processes are perpetuated through di erent pathways, in which adipose tissue is a major factor. High fat stores in overweight and obesity accumulate energy but the endocrine function is also producing and releasing diferent bioactive compounds, adipokines, known to be pro-inflammatory and which play an important role in the pathogenesis of asthma. This review therefore explores the latest evidence regarding the adverse e ect of theWestern diet on adipose tissue inflammation and its causative e ect on the asthma epidemic.