Browsing by Subject "Secondary metabolites"

Now showing 1 - 2 of 2
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    Allelopathic potential and chemical characterisation of ‘flor-de-papagaio’ bark (Norantea guianensis)
    (Universidad de Murcia. Servicio de publicaciones, 2021) Morbeck-de-Oliveira, Ademir Kleber; Matias, Rosemary; Lacerda-Pereira, Kelly Cristina; Silvia Rizz, Elvia; de Araújo Izaías-Muller, Jéssica
    El objetivo fue llevar a cabo la prospección fitoquímica de la cáscara de Norantea guianensis y evaluar su potencial alelopático en la germinación de semillas y el crecimiento inicial de plántulas de lechuga y tomate, utilizando extractos acuosos y etanólicos. Se identificaron compuestos fenólicos y sus derivados, flavonoides y taninos, así como cumarinas, antraquinonas, alcaloides y saponinas. Se produjo interferencia negativa en la germinación y el vigor, especialmente en las semillas de tomate, y los extractos afectaron negativamente el desarrollo de las plántulas. La especie N. guianensis tiene la capacidad de interferir en el desarrollo de otras plantas y por esta razón, su uso debe evaluarse cuidadosamente.
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    Biotechnological approaches to enhance the biosynthesis of ginkgolides and bilobalide in Ginkgo biloba
    (Springer, 2013-02-09) Sabater Jara, Ana Belén; Souliman Youssef, Sabry; Novo Uzal, Esther; Almagro, Lorena; Belchí Navarro, Sarai; Pedreño, María Ángeles; Biología Vegetal
    Ginkgo biloba is one of the oldest living tree species and its extracts or powdered leaves are one of the best selling herbal preparations. The main bioactive constituents are flavonoids and the terpene trilactones, ginkgolides and bilobalide, which are responsible for their pharmacological activity. However, there are many difficulties for ginkgo leaves supply and the chemical synthesis is far from of being applicable for commercial-scale production. G. biloba cell cultures have arisen as a useful alternative source of pharmacologically active terpene trilactones. This review sheds light on the chemistry and biosynthesis of terpene trilactones with the aim of increasing the production of these high value compounds by biotechnological approaches. Different biotechnological strategies to improve ginkgolides and bilobalide production will be discussed, including screening and selection of in vitro ginkgo cultures, cell differentiation levels of these cultures, optimization of culture conditions, feeding and elicitation strategies. Special attention will be paid in developing new methodologies to enhance ginkgo cell biomass and provide high amounts of these bioactive terpene trilactones using large-scale cell cultures.