Browsing by Subject "Menstrual cycle"

Now showing 1 - 2 of 2
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    Menstrual Cycle and Sport: effects on the performance and metabolism of the athlete woman
    (2022) Giménez-Blasi, Nuria; Latorre, Jose Antonio; Martínez-Bebia, Manuel; Sáenz, Marina; Cantero, Leticia; López-Moro, Alejandro; Jimenez-Casquet, Maria Jose; Conde-Pipo, Javier; Mariscal-Arcas, Miguel; Tecnología de Alimentos, Nutrición y Bromatología
    There are difficulties planning female training. The aim of this meta-analysis work is to know results obtained in studies on the relationship between the menstrual cycle (MC), diet, metabolism and performance in sportswomen. This work began in January-2022 looking differences in performance depending on the MC phase; exclusion criteria after 2015, non-experimental articles with quality indexes >Q2. We finally worked on 11 articles. Perception of the majority of sportswomen is that MC does have an impact on sports performance, as they are affected both physically and psychologically depending on the MC phase. Participant characteristics, such as training history, may also contribute to the variety of responses observed in studies. MC phase where performance may be reduced is in the Early Follicular Phase and may improve in the other MC phases. The effects found maybe of most relevance to female athletes
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    Regulation of human endometrial transforming growth factor ß1 and ß3 isoforms through menstrual cycle and medroxyprogesterone acetate treatment
    (Murcia : F. Hernández, 2002) Reis, F.M.; Ribeiro, M.F.M.; Maia, A.L.; Spritzer, P.M.
    The progesterone-induced differentiation of endometrial tissue from proliferative into secretory and decidua seems to be modulated by locally produced hormones and cytokines. Transforming growth factor beta (TGFß), a cytokine produced by endometrial cells, has been shown to modulate endometrial cell proliferation in vitro. Our aim was to evaluate the effects of medroxyprogesterone acetate (MPA) and the influence of menstrual cycle on the expression of TGFß1 and TGFß3 in human endometrium in vivo. In a doubleblind, placebo-controlled trial, 46 healthy women with regular menstrual cycles received either MPA (10 mg/day) or placebo during 10 days. Endometrial and blood samples were collected 8-12 hours after the last MPA or placebo administration. Patients were classified into three groups according to biopsy dating and treatment: proliferative [tissue]/placebo, secretory [tissue]/placebo and secretory [tissue]/MPA. The immunohistochemical distribution of TGFß1 and TGFß1 mRNA was similar in all groups. Immunoreactive TGFß3 was present in the epithelium in 9.1% of proliferative samples, in 41.2% of secretory/placebo samples and in 87.5% of secretory/MPA samples (p=0.001). In the stroma, the frequency of TGFß3 staining was markedly increased after treatment with MPA (62.5%) compared to placebo (proliferative: 9.1%; secretory: 5.9%; p=0.005). The levels of TGFß3 mRNA increased during the secretory phase and were higher in the MPA-treated group, being directly correlated with morphological endometrial differentiation. It is concluded that MPA administration to healthy women increased TGFß3 but did not change TGFß1 gene and protein expression in the endometrium. This finding suggests that TGFß3 may be a local factor mediating progesterone- and progestogen-induced endometrial differentiation.