Browsing by Subject "Low back pain"

Now showing 1 - 5 of 5
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    Animal models for disc degeneration-an update
    (Universidad de Murcia. Departamento de Biología Celular e Histología, 2018) Jin, Li; Balian, Gary; Li, Xudong Joshua
    Intervertebral disc degeneration is considered a major cause of back pain that places a heavy burden on society, both because of its effect on the physiology of individuals and its consequences on the world economy. During the past few decades, research findings in the pre-clinical setting have led to a significant increase in the understanding of intervertebral disc degeneration, although many aspects of the disease remain unclear. The goal of this review is to summarize existing animal models for disc degeneration studies and the difficulties that are associated with the use of such models. A firm understanding of the cellular and molecular events that ensue as a result of injuries, as well as environmental factors, could be instrumental in the development of targeted therapies for the treatment of intervertebral disc degeneration
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    Association between unilateral functional ankle instability, limited ankle dorsiflexion range of motion and low back pain
    (Universidad de Murcia, Servicio de Publicaciones, 2022) Abdelhaleem, Mahmoud Diab; Grase, Mariam Omran; Aly, Sobhy Mahmoud; Abdallah, Ehab Ali
    There is growing evidence that supports the correlation between incidence of ankle dysfunction and low back pain(LPB). Although the spine and ankle seem like distant regions of the body, they are functionally connected by the lower extremity kinematic chain. Theaim of the current study was to investigate the associationbetween functional ankle instability(FAI),limited ankle dorsiflexion (DF) range of motion (ROM) and(LPB).One hundred twosubjects with chronic ankle sprain pain participated in this study. The mean ± SD age, weight, height, and BMI of the study group were 43.5 ± 12.96 years, 85.27 ± 14.22 kg, 172.9 ± 8.45 cm, and 28.59 ± 4.72 kg/m². LPB was measured by Visual Analogue Scale (VAS), FAI was measured by the anterior drawer test and DFROM was measuredby the lunge test.All statistical analyses were performed using the Statistical Package for Social Studies (SPSS) version 25 for Windows. There was no statistically significant association between pain and age, pain and BMI, pain, and sex (p > 0.05). There was a statistically significant association between pain and drawer test (odd ratio 5.68, p = 0.02) and a statistically significant association between pain and DFROM (odd ratio 1.16, p = 0.01).The current study supportedprevious studies recommending FAIandlimited ankle DF ROM asa factor in LPB.The authors suggest conducting similar studies with a larger number of participants and include functional measures scales or questionnaires to increase the validity and generalizability of the results.
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    Back pain and knowledge on back care related to physical activity in 12 to 17 years old adolescents
    (MDPI, 2019-09-25) Aparicio Sarmiento, Alba; Rodríguez Ferrán, Olga; Martínez Romero, María Teresa; Cejudo Palomo, Antonio; Santonja Medina, Fernando; Sainz de Baranda Andújar, Pilar; Actividad Física y Deporte
    Knowledge on back care is important to prevent back problems. The purpose of this study was to a) describe back pain and knowledge on back care related to physical activity in adolescents and b) determine the association between these two factors. This was a cross-sectional study. A total of 276 students (aged from 12 to 17 years old), from three Spanish public secondary schools, had to complete a survey about back pain and another one about their knowledge on back care related to physical activity. The results showed a mean score of 2.54 ±1.85 (out of 10), and 90.58% of students failed the knowledge test. Those who suffered from back pain in the week before scored higher (2.91 ±1.66) than non-sufferers (2.42 ±1.90), with statistically significant differences (Z=−2.109; p= 0.035; r= 0.127), although with no academically relevant differences. Finally, despite the relationship between a higher mean score in the knowledge test and back pain within the previous week, it has been found that there was not a significant association because most of the students got very low scores in the knowledge test. It also shows an important lack of knowledge about physical activity for back care in adolescents.
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    Inflammatory mediators and signalling pathways controlling intervertebral disc degeneration
    (Universidad de Murcia. Departamento de Biología Celular e Histología, 2017) Navone, Stefania Elena; Marfia, Giovanni; Giannoni, Amedeo; Beretta, Matteo; Guarnaccia, Laura; Gualtierotti, Roberta; Nicoli, Daniele; Rampini, Paolo; Campanella, Rolando
    Intervertebral disc (IVD) degeneration (IDD) is one of the major causes of back pain, a condition that represents a serious socio-economic burden. Deeper knowledge of the complex and fine relationship between IVD degeneration, tissue inflammation and pain, appears to be critical to improve the current therapies, which have so far proven themselves ineffective. Upon degeneration, IVD tissues become inflamed, and this inflammatory microenvironment is associated with a cascade of degenerative events that may eventually cause discogenic pain. In particular, several studies have highlighted the major role of a number of proinflammatory mediators not only in the onset of the inflammatory condition, but also in the development of IDD in general. In this review, we will present the main pathological events that occur during disc degeneration, focusing on the relationship between the abnormal inflammatory milieu of the degenerating IVD, IDD and the generation of pain. Finally, we will present the current therapies for the treatment of IDD and low back pain, and the perspectives of future, more effective therapies.
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    Prevalence and characteristics of back pain in children and adolescents from the Region of Murcia (Spain): ISQUIOS programme
    (MDPI, 2022-01-15) Martínez Romero, María Teresa; Cejudo Palomo, Antonio; Sainz de Baranda Andújar, Pilar; Actividad Física y Deporte
    Puberty is a vulnerable period for musculoskeletal disorders due to the existence of a wide inter-individual variation in growth and development. The main objective of the present study was to describe the prevalence of back pain (BP) in the past year and month in school-aged children according to sex, age, maturity status, body mass index (BMI) and pain characteristics. This study involved 513 students aged between 9 and 16 years. Anthropometric measures were recorded to calculate the maturity stage of the students using a regression equation comprising measures for age, body mass, body height, sitting height and leg length. An ad hoc questionnaire composed of eight questions was used to describe BP prevalence in school-aged children. The results showed that the prevalence of BP in school-aged children was observed in 35.1% over the last year (45% boys and 55% girls), and 17.3% (40.4% boys and 59.6% girls, with an association found between female sex and BP) in the last month. The prevalence of back pain in the past year and month was higher the older the students were, or the more pubertal development they had experienced. The prevalence of BP in the last year was also higher in those with overweight or obesity. After adjustment for sex, there was an association between BP and older age and higher BMI in boys and an association between BP and higher pubertal development in girls. In summary, the present study showed that the prevalence of BP was related to the maturity stage and weight of the participants, with different prevalence patterns found according to sex.