(Murcia : F. Hernández, 1989) Poblador, María S.; Rojas, Carmen; Raya, Antonio; Quiralte, Joaquín; Casares, José A.; Lancho Alonso, José Luis
Cyclophosphamide administered at doses of 400
mg/m2/5 days with sacrifice two days later, and 200 mg/m2/5
days with a 21-day break and a further five days of
treatment, with sacrifice two days later, provokes similar
effects.
Functional activity is less marked in untreated and
control animals than in treated ones, as the hormone data
shows.
But the ultrastructure of PRL cells in treated animals
indicates the existence of clear hormone synthesis activity,
evident in the fusion and clustering of granules at differing
stages of maturity, etc.