(Murcia : F. Hernández, 1993) Carbajo, S.; Carvajal, J.C.; Rodríguez, J.; Carbajo-Pérez, E.
The expression of argyrophilic nucleolar
organizer regions (AgNORs) was studied in the anterior
lobe of the hypophysis of 1-, 7-, 14-, 28- and 80-day-old
rats. Mean area and numbers of AgNORs per nucleus
decreased during this period with a simultaneous
increase of both nuclear area and mean AgNOR-particle
area. Comparison of our data on AgNOR expression
with previously reported data on the proliferative
activity and cell maturation and differentiation of
anterior pituitary cells during a similar period led us to
conclude that, at least in our experimental model,
variations in the expression of AgNORs are more related
to phenomena of cellular maturation than to proliferative
activity.