(Murcia : F. Hernández, 1993) Aguirre, J.I.; Han, J.S.; Itagaki, S.; Doi, K.
Lectin histochernical characteristics of the
kidney of normal and streptozotocin (SZ)-induced
diabetic APA harnsters were investigated. Paraffin
sections of the kidney of animals killed at 1 and 3
rnonths after SZ-injection were stained with the following
10 lectins: PNA, BPA, DBA, SBA, GSA-1, GSA-11,
MPA, WGA, UEA-1 and Con A. Renal lectin binding
characteristics of normal APA harnsters differed in sorne
aspects from those in other species reported previously.
In the kidney of SZ-induced diabetic APA hamsters,
binding activities of sorne lectins increased in the
affected Bowman's capsules and glorneruli as well as in
degenerated epithelial cells of uriniferous tubules.
Among thern, GSA-11 in particular exhibited strong
binding activity to the degenerated epithelial cells of
Bowman's capsules, dista1 convoluted tubules and
collecting ducts.